STAGE IIIA BREAST CANCER
Clinical trials for STAGE IIIA BREAST CANCER explained in plain language.
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Breast cancer study: does adding trastuzumab to Pre-Surgery chemo improve outcomes?
Disease control CompletedThis phase II trial studied 92 women with early-stage breast cancer to see how well chemotherapy (paclitaxel and cyclophosphamide) with or without trastuzumab works before surgery. The main goals were to check side effects and see if the tumor disappears completely by the time of…
Matched conditions: STAGE IIIA BREAST CANCER
Phase: PHASE2 • Sponsor: University of Nebraska • Aim: Disease control
Last updated Jun 28, 2026 00:00 UTC
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Triple threat: new combo shows promise against tough breast cancer
Disease control CompletedThis phase II trial tested a combination of two targeted antibodies (pertuzumab and trastuzumab) plus a chemotherapy drug (nab-paclitaxel) in 63 patients with HER2-positive advanced breast cancer. The goal was to see how well the drugs work together to stop tumor growth and impro…
Matched conditions: STAGE IIIA BREAST CANCER
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New hope for Hard-to-Treat breast cancer? alisertib combo tested
Disease control CompletedThis phase II trial tested the drug alisertib, alone or combined with fulvestrant, in 96 postmenopausal women with advanced breast cancer that no longer responds to hormone therapy. Alisertib blocks enzymes that help cancer cells grow, while fulvestrant blocks estrogen. The goal …
Matched conditions: STAGE IIIA BREAST CANCER
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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New combo therapy shows promise in preventing breast cancer return
Disease control CompletedThis study looked at whether shutting down the ovaries (ovarian suppression) combined with hormone therapy (tamoxifen or exemestane) could better prevent breast cancer from coming back in premenopausal women with hormone-sensitive breast cancer. Over 3,000 women who had surgery t…
Matched conditions: STAGE IIIA BREAST CANCER
Phase: PHASE3 • Sponsor: ETOP IBCSG Partners Foundation • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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New drug combo offers hope for elderly breast cancer patients avoiding surgery
Disease control CompletedThis phase II trial tested a combination of hormone therapy drugs (fulvestrant or an aromatase inhibitor) plus palbociclib in 14 elderly patients with hormone-responsive breast cancer who either had inoperable tumors or were too frail for surgery. The goal was to see if this drug…
Matched conditions: STAGE IIIA BREAST CANCER
Phase: PHASE2 • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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Fish oil and arthritis drug tested against aggressive breast cancer in young women
Knowledge-focused CompletedThis early-phase study tested whether two anti-inflammatory drugs—fish oil (omega-3 fatty acid) and celecoxib (Celebrex)—could reduce inflammation and slow cancer growth in women aged 18-50 with pregnancy-associated breast cancer. The 42 participants took one of the drugs for at …
Matched conditions: STAGE IIIA BREAST CANCER
Phase: EARLY_PHASE1 • Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC