STAGE III OROPHARYNGEAL (P16-NEGATIVE) CARCINOMA AJCC V8
Clinical trials for STAGE III OROPHARYNGEAL (P16-NEGATIVE) CARCINOMA AJCC V8 explained in plain language.
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Blood test could Fine-Tune radiation for throat cancer patients
Disease control Recruiting nowThis study tests whether a blood test (NavDx) can help doctors decide the right amount of radiation for people with HPV-related throat cancer. The goal is to give enough treatment to control the cancer while reducing side effects. About 455 adults with certain stages of throat ca…
Matched conditions: STAGE III OROPHARYNGEAL (P16-NEGATIVE) CARCINOMA AJCC V8
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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New study explores best post-surgery treatment for head and neck cancer
Disease control Recruiting nowThis study compares radiation therapy alone to radiation plus the chemotherapy drug cisplatin for people with stage III-IVA head and neck cancer who have had surgery to remove their tumor. About 189 participants will be randomly assigned to one of the two treatments. The goal is …
Matched conditions: STAGE III OROPHARYNGEAL (P16-NEGATIVE) CARCINOMA AJCC V8
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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New drug combo aims to boost chemoradiation for head and neck cancer
Disease control Recruiting nowThis early-phase trial is testing whether adding the drug ipatasertib to standard chemotherapy and radiation can better control advanced head and neck cancer. Ipatasertib is a targeted therapy that may stop cancer cells from growing. The study involves about 46 adults with certai…
Matched conditions: STAGE III OROPHARYNGEAL (P16-NEGATIVE) CARCINOMA AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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Could a Two-Drug punch before surgery beat head and neck cancer?
Disease control Recruiting nowThis study tests whether adding an experimental drug (CDX-1140) to a standard immunotherapy (cemiplimab) before surgery can shrink advanced head and neck cancers more than the immunotherapy alone. About 44 people with stage III-IV head and neck cancer will receive either the comb…
Matched conditions: STAGE III OROPHARYNGEAL (P16-NEGATIVE) CARCINOMA AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 12, 2026 13:40 UTC
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New combo therapy aims to shrink tough cancers using biomarker clues
Disease control Recruiting nowThis study tests two drugs, cabozantinib and nivolumab, in people with advanced melanoma or head and neck cancer that hasn't responded to prior immunotherapy. The goal is to see if the combination can shrink or stabilize the cancer, and whether certain biomarkers in tumors can pr…
Matched conditions: STAGE III OROPHARYNGEAL (P16-NEGATIVE) CARCINOMA AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 11, 2026 20:50 UTC
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New drug aims to prevent painful mouth sores in head and neck cancer treatment
Symptom relief Recruiting nowThis phase 2 trial tests whether adding BMX-001 to standard care can reduce severe mouth sores caused by chemoradiation in head and neck cancer patients. About 98 participants will receive either BMX-001 or a placebo alongside usual mouth rinses and pain medication. The goal is t…
Matched conditions: STAGE III OROPHARYNGEAL (P16-NEGATIVE) CARCINOMA AJCC V8
Phase: PHASE2 • Sponsor: NRG Oncology • Aim: Symptom relief
Last updated May 15, 2026 09:28 UTC
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New imaging study reveals hidden vascular damage from radiation in head and neck cancer
Knowledge-focused Recruiting nowThis study uses special PET/CT scans to see how radiation therapy affects blood vessels in the neck of people with head and neck cancers. About 20 adults will get two types of PET scans before and after radiation. The goal is to compare the scans and learn more about radiation's …
Matched conditions: STAGE III OROPHARYNGEAL (P16-NEGATIVE) CARCINOMA AJCC V8
Phase: EARLY_PHASE1 • Sponsor: Emory University • Aim: Knowledge-focused
Last updated May 15, 2026 09:28 UTC
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Can a simple test detect throat cancer? mayo clinic launches biomarker hunt
Knowledge-focused Recruiting nowThis study aims to find a biological marker (biomarker) in blood, tissue, or saliva that shows up only when a person has HPV-related oropharyngeal cancer. Researchers will compare samples from 560 participants, including cancer patients and healthy controls, to see if the marker …
Matched conditions: STAGE III OROPHARYNGEAL (P16-NEGATIVE) CARCINOMA AJCC V8
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 14, 2026 12:06 UTC
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Can blood tests predict who will do their swallowing exercises?
Knowledge-focused Recruiting nowThis study looks at why people with head and neck cancer do or don't follow swallowing exercises after radiation. Researchers will use blood tests and questionnaires to see if immune system proteins or feelings about the illness affect exercise habits. The goal is to learn what h…
Matched conditions: STAGE III OROPHARYNGEAL (P16-NEGATIVE) CARCINOMA AJCC V8
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated May 12, 2026 13:43 UTC