STAGE IIB PANCREATIC CANCER AJCC V8

This study tests a combination of two chemotherapy drugs and two immunotherapy drugs given before surgery to people with pancreatic cancer that can be removed. The goal is to shrink the tumor and help the immune system fight the cancer, potentially improving outcomes. The trial i…

This study tests whether a combination of two drugs, lenvatinib and pembrolizumab, can help keep advanced pancreatic cancer from getting worse. The trial involves 28 adults whose cancer has spread and cannot be surgically removed, and who have already responded to initial treatme…

This study tests a new method called sonoporation, which uses ultrasound and tiny gas bubbles to help chemotherapy drugs get into cancer cells more effectively. The trial includes 120 adults with advanced or hard-to-remove pancreatic cancer who are already receiving standard chem…

This early-stage trial tests two drugs together for people with advanced pancreatic cancer. One drug starves cancer cells by removing a key nutrient, while the other blocks a protein that helps them grow. The goal is to find the safest dose and see if the combination can control …

This early-phase study tests whether adding the blood pressure drug losartan to a shorter, stronger course of radiation therapy can help treat pancreatic cancer that is either borderline removable or has spread locally. Losartan may improve blood flow and oxygen in the tumor, mak…