STAGE IIA BREAST CANCER
Clinical trials for STAGE IIA BREAST CANCER explained in plain language.
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Immune booster before chemo shows promise for tough breast cancer
Disease control OngoingThis study tests whether giving two immunotherapy drugs (decitabine and pembrolizumab) before standard chemotherapy can help the immune system attack HER2-negative breast cancer more effectively. About 46 adults with locally advanced disease will receive a short course of these d…
Matched conditions: STAGE IIA BREAST CANCER
Phase: PHASE2 • Sponsor: Virginia Commonwealth University • Aim: Disease control
Last updated Jul 02, 2026 03:00 UTC
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One-Time radiation boost during breast surgery shows promise in Early-Stage cancer trial
Disease control OngoingThis study tests whether giving a single dose of radiation directly to the tumor site during breast-conserving surgery (lumpectomy) and before reconstruction is safe and effective for women with early-stage breast cancer. About 108 participants with stage I-II breast cancer will …
Matched conditions: STAGE IIA BREAST CANCER
Phase: PHASE2 • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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New hope for tough breast cancer: which chemo works best after surgery?
Disease control OngoingThis study tests whether platinum-based chemotherapy (cisplatin or carboplatin) works better than capecitabine in people with a certain type of triple-negative breast cancer that remains after initial chemotherapy and surgery. About 415 participants with stage II-III breast cance…
Matched conditions: STAGE IIA BREAST CANCER
Phase: PHASE3 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Could adding carboplatin to chemo keep triple-negative breast cancer away?
Disease control OngoingThis phase 3 trial tests whether adding the drug carboplatin to standard chemotherapy (doxorubicin, cyclophosphamide, and paclitaxel) helps prevent triple-negative breast cancer from coming back. About 782 patients with high-risk or node-positive disease are participating. The st…
Matched conditions: STAGE IIA BREAST CANCER
Phase: PHASE3 • Sponsor: NRG Oncology • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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New chemo combo aims to shrink aggressive breast cancer before surgery
Disease control OngoingThis phase II trial is testing whether giving two chemotherapy drugs, carboplatin and nab-paclitaxel, before surgery can improve outcomes for people with locally advanced or inflammatory triple negative breast cancer. The goal is to see if this approach increases the rate of comp…
Matched conditions: STAGE IIA BREAST CANCER
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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Single dose of radiation during lumpectomy may control early breast cancer
Disease control OngoingThis study tests giving a single dose of radiation directly to the tumor site during breast-conserving surgery for early-stage breast cancer. The goal is to see if this one-time treatment works as well as standard radiation therapy that requires multiple visits. Over 1,200 partic…
Matched conditions: STAGE IIA BREAST CANCER
Phase: NA • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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Shorter radiation after mastectomy may cut side effects
Disease control OngoingThis phase III trial tests whether a shorter course of radiation (hypofractionated) after mastectomy can prevent cancer recurrence with fewer side effects than standard radiation. About 900 patients with stage II-IIIa breast cancer are participating. The study compares complicati…
Matched conditions: STAGE IIA BREAST CANCER
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC