STAGE IA BREAST CANCER
Clinical trials for STAGE IA BREAST CANCER explained in plain language.
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Breast cancer study: does adding trastuzumab to Pre-Surgery chemo improve outcomes?
Disease control CompletedThis phase II trial studied 92 women with early-stage breast cancer to see how well chemotherapy (paclitaxel and cyclophosphamide) with or without trastuzumab works before surgery. The main goals were to check side effects and see if the tumor disappears completely by the time of…
Matched conditions: STAGE IA BREAST CANCER
Phase: PHASE2 • Sponsor: University of Nebraska • Aim: Disease control
Last updated Jun 28, 2026 00:00 UTC
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New combo therapy shows promise in preventing breast cancer return
Disease control CompletedThis study looked at whether shutting down the ovaries (ovarian suppression) combined with hormone therapy (tamoxifen or exemestane) could better prevent breast cancer from coming back in premenopausal women with hormone-sensitive breast cancer. Over 3,000 women who had surgery t…
Matched conditions: STAGE IA BREAST CANCER
Phase: PHASE3 • Sponsor: ETOP IBCSG Partners Foundation • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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Breast cancer radiation cut to just 9 days in new trial
Disease control CompletedThis phase II trial tested a 9-day course of whole breast radiation (hypofractionated radiotherapy) in 102 patients with early-stage breast cancer (stage 0-IIB). The goal was to see if a shorter treatment time could maintain effectiveness while reducing side effects. Researchers …
Matched conditions: STAGE IA BREAST CANCER
Phase: PHASE2 • Sponsor: University of Utah • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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New drug combo offers hope for elderly breast cancer patients avoiding surgery
Disease control CompletedThis phase II trial tested a combination of hormone therapy drugs (fulvestrant or an aromatase inhibitor) plus palbociclib in 14 elderly patients with hormone-responsive breast cancer who either had inoperable tumors or were too frail for surgery. The goal was to see if this drug…
Matched conditions: STAGE IA BREAST CANCER
Phase: PHASE2 • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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Could a short course of radiation before surgery spare more breast tissue?
Disease control CompletedThis pilot study tested whether giving a high dose of focused radiation (APBI) to the tumor before surgery is feasible for older women with early-stage, hormone-sensitive breast cancer. Twenty-two participants received radiation followed by a lumpectomy. The goal was to see if th…
Matched conditions: STAGE IA BREAST CANCER
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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MRI before breast surgery: game changer or unnecessary extra?
Knowledge-focused CompletedThis study looked at whether women with early-stage breast cancer benefit from having a breast MRI in addition to standard mammograms before surgery. Researchers tracked 319 women to see if the MRI helped reduce the chance of cancer coming back, lowered the need for repeat surger…
Matched conditions: STAGE IA BREAST CANCER
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Knowledge-focused
Last updated Jun 28, 2026 00:00 UTC
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Fish oil and arthritis drug tested against aggressive breast cancer in young women
Knowledge-focused CompletedThis early-phase study tested whether two anti-inflammatory drugs—fish oil (omega-3 fatty acid) and celecoxib (Celebrex)—could reduce inflammation and slow cancer growth in women aged 18-50 with pregnancy-associated breast cancer. The 42 participants took one of the drugs for at …
Matched conditions: STAGE IA BREAST CANCER
Phase: EARLY_PHASE1 • Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC