STAGE I BREAST CANCER

This study looks at whether aerobic exercise can lower ctDNA levels in the blood, which may help prevent cancer from returning. About 33 people who have been treated for high-risk breast, prostate, or colorectal cancer will try different amounts of weekly exercise to find the saf…

This study compares a 1-week radiation schedule to the standard 3-week schedule for people with early-stage breast cancer who have had breast-conserving surgery. The goal is to see if the shorter treatment works just as well at controlling cancer and has fewer side effects. About…

This study tests two drugs, niraparib and dostarlimab, given before surgery to people with BRCA- or PALB2-mutated breast cancer. The goal is to see if this combination boosts the immune system's attack on the tumor and leads to a complete response (no cancer left at surgery). Abo…

This study tests whether a single, focused radiation treatment works as well as five treatments for people with low-risk stage 0 or I breast cancer after a lumpectomy. About 134 participants will be randomly assigned to receive either one or five doses of radiation to the tumor a…

This study explores whether acupuncture can improve memory, focus, and thinking problems (often called 'chemo brain') in people who have finished treatment for breast, colorectal, prostate, or gynecologic cancer. About 48 participants will receive acupuncture sessions, and resear…