STAGE I BLADDER CANCER AJCC V8
Clinical trials for STAGE I BLADDER CANCER AJCC V8 explained in plain language.
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Immunotherapy vs chemo: new hope for bladder cancer patients?
Disease control Recruiting nowThis phase II trial compares two treatments for high-grade T1 bladder cancer that hasn't spread. One group gets the immunotherapy drug pembrolizumab plus radiation, while the other gets standard chemotherapy (cisplatin, gemcitabine, 5-fluorouracil, or mitomycin-C) plus radiation.…
Matched conditions: STAGE I BLADDER CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Bladder cancer combo trial: could adding chemo to BCG keep tumors away?
Disease control Recruiting nowThis phase 3 trial tests whether adding the chemotherapy drug gemcitabine to standard BCG therapy can better prevent high-grade bladder cancer from coming back. About 330 people with recurrent non-muscle invasive bladder cancer will receive either BCG alone or BCG plus gemcitabin…
Matched conditions: STAGE I BLADDER CANCER AJCC V8
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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New nanoparticle therapy targets bladder cancer cells
Disease control Recruiting nowThis early-stage trial tests a new treatment called PLZ4-coated paclitaxel-loaded micelles (PPM) for people with non-muscle invasive bladder cancer that has come back or not responded to standard therapy. PPM is a nanoparticle designed to deliver chemotherapy directly to tumor ce…
Matched conditions: STAGE I BLADDER CANCER AJCC V8
Phase: PHASE1 • Sponsor: University of California, Davis • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
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New vaccine combo aims to train immune system to fight bladder cancer
Disease control Recruiting nowThis early-stage trial is testing a new peptide vaccine (IO102-IO103) combined with the immunotherapy drug pembrolizumab (Keytruda) in 30 adults with high-risk non-muscle invasive bladder cancer that did not respond to or could not tolerate standard BCG therapy. The vaccine is de…
Matched conditions: STAGE I BLADDER CANCER AJCC V8
Phase: PHASE1 • Sponsor: University of California, Davis • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Bladder cancer chemotherapy comes home: new trial tests convenience and safety
Symptom relief Recruiting nowThis study tests whether giving chemotherapy directly into the bladder at home is safe and acceptable for people with non-muscle invasive bladder cancer. About 40 participants will receive their usual medications—such as BCG, gemcitabine, docetaxel, or mitomycin—at home instead o…
Matched conditions: STAGE I BLADDER CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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Bladder cancer patients step up: App-Based exercise trial aims to boost activity
Symptom relief Recruiting nowThis study compares a home-based physical activity program delivered through the ExerciseRx app to health education alone in 100 adults with non-muscle invasive bladder cancer. Participants will use a Fitbit to track steps, and the app will set personalized goals and provide enco…
Matched conditions: STAGE I BLADDER CANCER AJCC V8
Phase: NA • Sponsor: University of Washington • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC