SQUAMOUS CELL CARCINOMA OF THE ORAL CAVITY
Clinical trials for SQUAMOUS CELL CARCINOMA OF THE ORAL CAVITY explained in plain language.
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Could fewer radiation sessions after surgery improve quality of life for head and neck cancer patients?
Disease control OngoingThis study tests a shorter, more intense course of radiation therapy (hypofractionated IMRT) given after surgery for head and neck cancer. The goal is to see if it is safe and if it can help patients maintain better swallowing function compared to the standard longer radiation sc…
Matched conditions: SQUAMOUS CELL CARCINOMA OF THE ORAL CAVITY
Phase: PHASE1, PHASE2 • Sponsor: University of Texas Southwestern Medical Center • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Immunotherapy combo shows promise in shrinking oral tumors before surgery
Disease control OngoingThis study tests two immunotherapy drugs, nivolumab and ipilimumab, given before surgery to people with oral cavity squamous cell carcinoma. The goal is to see if these drugs can shrink tumors and are safe to use. About 30 adults with tumors larger than 2 cm or lymph node involve…
Matched conditions: SQUAMOUS CELL CARCINOMA OF THE ORAL CAVITY
Phase: PHASE2 • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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New drug aims to spare cancer patients from debilitating mouth sores
Symptom relief OngoingThis phase 2 trial tests whether the drug RRx-001 can prevent severe oral mucositis (painful mouth sores) in 216 patients with head and neck cancer receiving standard chemoradiation. Patients are randomly assigned to receive RRx-001 or a placebo alongside their usual treatment. T…
Matched conditions: SQUAMOUS CELL CARCINOMA OF THE ORAL CAVITY
Phase: PHASE2 • Sponsor: EpicentRx, Inc. • Aim: Symptom relief
Last updated Jun 28, 2026 00:00 UTC
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Could a DNA swab after surgery predict Cancer's return?
Knowledge-focused OngoingThis study looks at whether testing the surgical wound for leftover tumor DNA can help predict if oral cancer will come back. Researchers will check for this DNA in 31 patients after their tumor is removed. The goal is to see if this test gives useful information beyond standard …
Matched conditions: SQUAMOUS CELL CARCINOMA OF THE ORAL CAVITY
Phase: NA • Sponsor: Centre Henri Becquerel • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC