SPINAL MUSCULAR ATROPHY TYPE 3
Clinical trials for SPINAL MUSCULAR ATROPHY TYPE 3 explained in plain language.
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New Muscle-Boosting drug shows promise for SMA patients in major trial
Disease control CompletedThis Phase 3 trial tested apitegromab, a drug that blocks a muscle-limiting protein, in 188 nonambulatory children and young adults with later-onset spinal muscular atrophy (SMA types 2 and 3). All participants were already taking standard SMA therapies (nusinersen or risdiplam).…
Matched conditions: SPINAL MUSCULAR ATROPHY TYPE 3
Phase: PHASE3 • Sponsor: Scholar Rock, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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New drug shows promise for improving walking in adults with spinal muscular atrophy
Symptom relief CompletedThis study tested an experimental drug called NMD670 in 52 adults with type 3 spinal muscular atrophy who can still walk. The goal was to see if the drug helps them walk farther in 6 minutes and improves muscle strength compared to a placebo. The trial is now complete, and result…
Matched conditions: SPINAL MUSCULAR ATROPHY TYPE 3
Phase: PHASE2 • Sponsor: NMD Pharma A/S • Aim: Symptom relief
Last updated Jun 27, 2026 13:01 UTC
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Spinal zap trial aims to help SMA patients move better
Symptom relief CompletedThis small pilot study tested whether a temporary spinal cord stimulator (like a pacemaker for the spine) could help people with spinal muscular atrophy types 3 and 4 move their legs better. Three adults who could stand independently received the implant for up to 29 days. The go…
Matched conditions: SPINAL MUSCULAR ATROPHY TYPE 3
Phase: NA • Sponsor: Marco Capogrosso • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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New tests could reveal how SMA progresses in adults
Knowledge-focused CompletedThis study looked at 67 adults with spinal muscular atrophy (SMA) types 2 and 3 to see if special electrical tests (MUNE and CMAP) can track nerve loss over time. The goal was to find better ways to measure how the disease changes, not to test a treatment. Participants had geneti…
Matched conditions: SPINAL MUSCULAR ATROPHY TYPE 3
Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC