SOLID TUMOR MALIGNANCIES
Clinical trials for SOLID TUMOR MALIGNANCIES explained in plain language.
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New targeted drug trial aims to slow advanced cancers by fixing genetic switches
Disease control Not yet recruitingThis study is testing an investigational pill called valemetostat for adults with advanced solid tumors that have stopped responding to standard treatments. It is specifically for people whose cancers have certain genetic changes affecting a cellular system called SWI/SNF. The go…
Matched conditions: SOLID TUMOR MALIGNANCIES
Phase: PHASE2 • Sponsor: Gustave Roussy, Cancer Campus, Grand Paris • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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Custom mRNA vaccine trial opens for advanced cancer patients
Disease control Not yet recruitingThis early study is testing a personalized mRNA vaccine called RH125 for people with advanced solid tumors who have run out of standard treatment options. Researchers will give the vaccine alone or combined with a PD-1 blocker drug to 36 patients to check if it's safe and to see …
Matched conditions: SOLID TUMOR MALIGNANCIES
Phase: EARLY_PHASE1 • Sponsor: Cancer Hospital Chinese Academy of Medical Science, Shenzhen Center • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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New pill targets advanced cancers in major trial
Disease control Not yet recruitingThis study is testing a new oral drug called TYK-01054 in people with advanced solid tumors that have spread or cannot be removed by surgery. The main goals are to find a safe and effective dose and to see if the drug can help control the cancer. The trial will enroll adults whos…
Matched conditions: SOLID TUMOR MALIGNANCIES
Phase: PHASE1, PHASE2 • Sponsor: TYK Medicines, Inc • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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Early test: can a common acid boost cancer treatment?
Disease control Not yet recruitingThis early-stage study aims to see if adding an oral malic acid supplement to standard immunotherapy is safe and might help control solid tumors like lung or colorectal cancer. It will involve about 30 adults already receiving immunotherapy. Researchers will check for side effect…
Matched conditions: SOLID TUMOR MALIGNANCIES
Phase: EARLY_PHASE1 • Sponsor: The First Affiliated Hospital of Xinxiang Medical College • Aim: Disease control
Last updated Mar 23, 2026 15:14 UTC
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Could this drug save cancer Patients' hearing?
Symptom relief Not yet recruitingThis study is testing if a drug called Pedmark® can protect hearing in adults receiving cisplatin chemotherapy, a common cancer treatment that often causes permanent hearing loss. The drug is already approved for children, but this trial will see if it's safe and effective for ad…
Matched conditions: SOLID TUMOR MALIGNANCIES
Phase: PHASE1, PHASE2 • Sponsor: University of Arizona • Aim: Symptom relief
Last updated Mar 10, 2026 12:53 UTC
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Scientists hunt for early warning signs of dangerous cancer drug reactions
Knowledge-focused Not yet recruitingThis study aims to find biological markers that can predict which cancer patients are likely to experience severe side effects from immunotherapy drugs. Researchers will collect various blood and health data from 160 adults with solid tumors before and after they start standard i…
Matched conditions: SOLID TUMOR MALIGNANCIES
Phase: NA • Sponsor: Assistance Publique Hopitaux De Marseille • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:34 UTC
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Scientists hunt for blood test to predict cancer Patients' mental health risk
Knowledge-focused Not yet recruitingThis study aims to find biological markers in blood and tumor tissue that are linked to anxiety and depression in people with solid tumors. Researchers will enroll 100 cancer patients, assess their mental health, and analyze their samples. The goal is to create a tool to help doc…
Matched conditions: SOLID TUMOR MALIGNANCIES
Sponsor: The First Affiliated Hospital of Xinxiang Medical College • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:02 UTC