SOFT TISSUE SARCOMA (STS)

This study tests whether a higher dose of proton radiation can better control soft tissue sarcomas that cannot be surgically removed. About 40 adults in Norway will receive radiation over 4 weeks, with the highest dose focused on the tumor center. Researchers will also look at bl…

This study tests a new oral drug called cirtuvivint for people with advanced soft-tissue sarcoma that has not responded to prior treatment. About 25 participants in Spain will take the drug to see if it can stop or slow tumor growth for at least 3 months. The drug is still experi…

This study compares a new type of radiation therapy (SFRT) to standard radiation for people with large soft tissue sarcomas (tumors at least 5 cm). About 106 adults aged 18-70 will be randomly assigned to one of the two treatments. The goal is to see if SFRT can shrink tumors bet…

This study looks at tissue and imaging data from 800 people with high-risk soft tissue sarcoma to find ways to personalize chemotherapy. Participants either have surgery alone or chemo before surgery. The goal is to build a tumor atlas and a tool to predict who benefits from chem…

This study is testing whether a new radioactive imaging agent can safely and clearly show tumors in people with many types of solid cancers. About 32 adults will receive a single injection of the agent and then have PET/CT scans to see where it goes in the body. The goal is to le…

This study collects fluid from the lungs of 70 people with soft-tissue sarcoma that has spread to the lungs. Researchers will look for specific markers in the fluid to see if they can predict how the disease will progress. The goal is to better understand the body's immune respon…