SLE
Clinical trials for SLE explained in plain language.
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New lupus drug shows promise in Mid-Stage trial
Disease control OngoingThis study tests an experimental drug called ESK-001 in about 408 adults with active lupus. Participants receive either the drug or a placebo to see if it safely reduces disease activity over 48 weeks. The goal is to find a better treatment option for managing lupus.
Matched conditions: SLE
Phase: PHASE2 • Sponsor: Alumis Inc • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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Immune cell therapy shows promise for tough lupus cases
Disease control OngoingThis early-stage study tests a new treatment called AB-101, made from natural killer cells, combined with antibody therapy for people with lupus nephritis or other hard-to-treat lupus. The goal is to see if it is safe and can help when standard treatments have failed. About 51 ad…
Matched conditions: SLE
Phase: PHASE1 • Sponsor: Artiva Biotherapeutics, Inc. • Aim: Disease control
Last updated May 11, 2026 20:37 UTC
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CAR-T therapy for autoimmune diseases: trial pulled before start
Disease control TerminatedThis early-phase trial aimed to test a CD19-targeted CAR-T cell therapy (RD06-04) in people with autoimmune diseases like lupus, multiple sclerosis, and myasthenia gravis. The goal was to see if the treatment was safe and could reduce disease activity. However, the study was with…
Matched conditions: SLE
Phase: EARLY_PHASE1 • Sponsor: Nanjing Bioheng Biotech Co., Ltd. • Aim: Disease control
Last updated May 04, 2026 16:20 UTC
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Lupus flare may swell heart muscle, MRI study aims to find out
Knowledge-focused OngoingThis study looks at whether lupus flares cause swelling in the heart muscle. Researchers will use cardiac MRI to check 40 adults with active lupus for heart inflammation during a flare and again 3 months later. The goal is to better understand how lupus affects the heart.
Matched conditions: SLE
Sponsor: Stacy Ardoin MD • Aim: Knowledge-focused
Last updated Apr 26, 2026 19:38 UTC