SLE
Clinical trials for SLE explained in plain language.
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Community leaders step up to boost COVID shots in black rheumatic patients
⭐️ VACCINE ⭐️ OngoingThis study tests whether training popular community leaders to share vaccine information can increase COVID-19 booster shots among Black individuals with rheumatic conditions like lupus. About 60 people will take part, including leaders and their social network members. The goal …
Matched conditions: SLE
Phase: NA • Sponsor: Northwestern University • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 27, 2026 13:00 UTC
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New lupus pill shows promise in Mid-Stage trial
Disease control OngoingThis Phase 2 study tests an experimental oral drug called ESK-001 in 408 adults with active systemic lupus erythematosus (SLE). Participants receive either ESK-001 or a placebo for 48 weeks to see if the drug can reduce disease activity. The goal is to find a new treatment option…
Matched conditions: SLE
Phase: PHASE2 • Sponsor: Alumis Inc • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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Immune cell therapy aimed at autoimmune diseases hits early snag
Disease control TerminatedThis early-phase trial planned to test a one-time infusion of genetically modified immune cells (CAR-T cells) targeting CD19 in people with several autoimmune diseases, including lupus and multiple sclerosis. The goal was to see if it was safe and could reduce harmful antibodies.…
Matched conditions: SLE
Phase: EARLY_PHASE1 • Sponsor: Nanjing Bioheng Biotech Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 09:01 UTC
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Immune cell therapy shows promise for tough lupus cases
Disease control OngoingThis early-stage study tests a new treatment called AB-101 for people with lupus nephritis or other hard-to-treat lupus. AB-101 uses donated natural killer cells to boost the body's ability to fight the disease. The study aims to see if this approach is safe and can help patients…
Matched conditions: SLE
Phase: PHASE1 • Sponsor: Artiva Biotherapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Lupus flare may trigger hidden heart swelling, MRI study hints
Knowledge-focused OngoingThis study looks at whether lupus flares cause swelling in the heart muscle. Researchers will use cardiac MRI to scan 40 lupus patients during a flare and again three months later. The goal is to better understand heart inflammation in lupus, not to test a new treatment.
Matched conditions: SLE
Sponsor: Stacy Ardoin MD • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC