RESTLESS LEGS SYNDROME
Clinical trials for RESTLESS LEGS SYNDROME explained in plain language.
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Could a methadone derivative ease restless legs?
Symptom relief TerminatedThis study tests a drug called d-methadone in 50 people with moderate to very severe restless legs syndrome (RLS). Participants take the drug or a placebo daily for 30 days. The goal is to see if it reduces RLS symptoms and improves sleep quality.
Matched conditions: RESTLESS LEGS SYNDROME
Phase: PHASE2 • Sponsor: Mauro Manconi • Aim: Symptom relief
Last updated May 16, 2026 04:49 UTC
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Restless legs in rare disease: new hope for better sleep and walking
Symptom relief OngoingThis study looks at how common restless leg syndrome is in women with X-linked adrenoleukodystrophy (ALD) and tests if the drug pramipexole can reduce leg symptoms, improve sleep, and help with walking. About 24 women with ALD will take part. The goal is to see if treating restle…
Matched conditions: RESTLESS LEGS SYNDROME
Phase: PHASE4 • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated May 14, 2026 12:04 UTC
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Vibration therapy offers new hope for dialysis patients with restless legs
Symptom relief OngoingThis study tests whether a simple vibration therapy applied to the calf muscles can reduce the intensity of restless legs syndrome (RLS) and improve sleep in people undergoing hemodialysis. Seventy participants will receive vibration therapy for 10 minutes per session, twice a we…
Matched conditions: RESTLESS LEGS SYNDROME
Phase: NA • Sponsor: Amjed Abdulabbas Shraida • Aim: Symptom relief
Last updated May 13, 2026 16:03 UTC