REFRACTORY OSTEOSARCOMA
Clinical trials for REFRACTORY OSTEOSARCOMA explained in plain language.
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Experimental combo aims to tackle tough bone cancer
Disease control Recruiting nowThis early-stage trial tests a new drug called tegavivint combined with the chemotherapy gemcitabine in 24 people whose osteosarcoma (a type of bone cancer) has returned or not responded to prior treatment. The main goal is to find the safest dose of tegavivint when given with ge…
Matched conditions: REFRACTORY OSTEOSARCOMA
Phase: PHASE1 • Sponsor: Emory University • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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New hope for kids with tough cancers: Two-Drug attack on tumors
Disease control Recruiting nowThis study is for children and young adults (ages 1 to 30) whose solid tumors have come back or not gone away with standard treatment. It tests two different drug pairs: one combines Onivyde with talazoparib, the other Onivyde with temozolomide. Both work by damaging cancer cell …
Matched conditions: REFRACTORY OSTEOSARCOMA
Phase: PHASE1, PHASE2 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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New hope for young cancer patients: experimental drug targets recurrent tumors
Disease control Recruiting nowThis study tests a drug called tegavivint in children, teens, and young adults whose solid tumors have come back or stopped responding to treatment. The goal is to find the safest dose and see if it can shrink tumors by blocking a key growth signal inside cancer cells. About 147 …
Matched conditions: REFRACTORY OSTEOSARCOMA
Phase: PHASE1, PHASE2 • Sponsor: Children's Oncology Group • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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New drug combo aims to control aggressive bone cancer in young patients
Disease control Recruiting nowThis study tests two drugs, atezolizumab and cabozantinib, in 40 adolescents and young adults (ages 12 and up) with osteosarcoma that has come back or spread. Atezolizumab helps the immune system attack cancer cells, while cabozantinib blocks enzymes that help tumors grow. The go…
Matched conditions: REFRACTORY OSTEOSARCOMA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:09 UTC
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Engineered immune cells take on tough bone cancer in first human test
Disease control Recruiting nowThis early-stage trial is testing a new type of immune cell therapy called FH-FOLR1 ST CAR T-cells for people with advanced osteosarcoma that has come back or not responded to treatment. The therapy involves taking a patient's own immune cells, modifying them in a lab to recogniz…
Matched conditions: REFRACTORY OSTEOSARCOMA
Phase: PHASE1 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
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Immune cell combo shows promise for tough childhood cancers
Disease control Recruiting nowThis early-phase trial is testing whether giving children with advanced neuroblastoma or osteosarcoma a special type of immune cell (gamma delta T cells) from a healthy donor, along with several standard cancer drugs, is safe and tolerable. The study will enroll 24 children aged …
Matched conditions: REFRACTORY OSTEOSARCOMA
Phase: PHASE1 • Sponsor: Emory University • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC