REFRACTORY NEUROBLASTOMA
Clinical trials for REFRACTORY NEUROBLASTOMA explained in plain language.
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New hope for kids with tough cancers: experimental drug PEEL-224 enters trials
Disease control Recruiting nowThis study tests a new drug called PEEL-224, alone or with standard chemotherapy, in children and young adults whose solid tumors have not responded to treatment or have returned. The first part finds the safest dose, and the second part measures how well the drug combination shr…
Matched conditions: REFRACTORY NEUROBLASTOMA
Phase: PHASE1, PHASE2 • Sponsor: Theodore Laetsch • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New hope for kids with tough cancers: Two-Drug attack on tumors
Disease control Recruiting nowThis study is for children and young adults (ages 1 to 30) whose solid tumors have come back or not gone away with standard treatment. It tests two different drug pairs: one combines Onivyde with talazoparib, the other Onivyde with temozolomide. Both work by damaging cancer cell …
Matched conditions: REFRACTORY NEUROBLASTOMA
Phase: PHASE1, PHASE2 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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Engineered immune cells take aim at childhood cancer
Disease control Recruiting nowThis study tests a new treatment for children and young adults with neuroblastoma that has returned or not responded to standard care. The treatment uses specially engineered immune cells from donated cord blood that are designed to recognize and attack two different markers on t…
Matched conditions: REFRACTORY NEUROBLASTOMA
Phase: PHASE1, PHASE2 • Sponsor: Beijing Biotech • Aim: Disease control
Last updated Jun 27, 2026 12:02 UTC
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Engineered immune cells take on childhood cancers in first human trial
Disease control Recruiting nowThis early-stage trial is testing a new treatment called GPC2 CAR T cells for children with neuroblastoma or retinoblastoma that has come back or not responded to standard treatments. The therapy uses a patient's own immune cells, which are modified in a lab to better recognize a…
Matched conditions: REFRACTORY NEUROBLASTOMA
Phase: PHASE1 • Sponsor: Stephan Grupp MD PhD • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Engineered immune cells take on childhood cancer in new trial
Disease control Recruiting nowThis trial tests a new treatment called hALK.CAR T cells for children and young adults with high-risk neuroblastoma that has returned or not responded to standard treatments. The therapy involves taking a patient's own immune cells, engineering them to recognize and attack cancer…
Matched conditions: REFRACTORY NEUROBLASTOMA
Phase: PHASE1, PHASE2 • Sponsor: Roberto Chiarle • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Immune cell combo shows promise for tough childhood cancers
Disease control Recruiting nowThis early-phase trial is testing whether giving children with advanced neuroblastoma or osteosarcoma a special type of immune cell (gamma delta T cells) from a healthy donor, along with several standard cancer drugs, is safe and tolerable. The study will enroll 24 children aged …
Matched conditions: REFRACTORY NEUROBLASTOMA
Phase: PHASE1 • Sponsor: Emory University • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC