PROGNOSTIC STAGE IV BREAST CANCER AJCC V8
Clinical trials for PROGNOSTIC STAGE IV BREAST CANCER AJCC V8 explained in plain language.
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Scientists test new 'In-Situ' cancer vaccine strategy
Disease control OngoingThis early-stage trial is testing the safety of a new combination treatment for people with advanced cancers that have spread and cannot be removed by surgery. Doctors inject immune-stimulating drugs directly into a tumor, then give a small dose of radiation to that same spot. Th…
Matched conditions: PROGNOSTIC STAGE IV BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: University of Southern California • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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New drug combo tested for Tough-to-Treat advanced cancers
Disease control OngoingThis early-stage study is testing a new combination of two drugs, AZD8186 and docetaxel, for patients with advanced solid tumors that have specific genetic changes (PTEN or PIK3CB mutations). The main goals are to find the safest and most effective dose and to understand the side…
Matched conditions: PROGNOSTIC STAGE IV BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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Double attack on tough cancers: early trial tests combo for patients out of options
Disease control OngoingThis early-stage trial is testing a combination of two drugs, niraparib and dostarlimab, for people with advanced breast, ovarian, pancreatic, or related cancers that have a specific genetic change (BRCA mutation) and have stopped responding to standard treatments. The goal is to…
Matched conditions: PROGNOSTIC STAGE IV BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: University of Washington • Aim: Disease control
Last updated Mar 23, 2026 15:16 UTC
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Scientists test Cancer-Killing virus in patients with Tough-to-Treat breast cancer
Disease control OngoingThis is a first-in-human, early-stage safety study testing a new type of cancer treatment called an oncolytic virus. The virus, called CF33-hNIS-antiPDL1, is designed to be injected directly into tumors to infect and break down cancer cells, while also potentially helping the pat…
Matched conditions: PROGNOSTIC STAGE IV BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Feb 23, 2026 14:55 UTC
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New scan aims to spot if breast cancer treatment is working sooner
Diagnosis OngoingThis study is testing whether a special type of PET/CT scan can better measure how well treatment is working for breast cancer that has spread to the bones. About 138 patients with this type of advanced cancer will get the scan before starting treatment and again 12 weeks later. …
Matched conditions: PROGNOSTIC STAGE IV BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Diagnosis
Last updated Apr 01, 2026 14:41 UTC
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Can blood tests tame Chemo's painful side effects?
Knowledge-focused TerminatedThis study aims to see if doctors can reliably measure the amount of a common chemotherapy drug (paclitaxel) in a patient's blood. The goal is to learn if tracking these levels can help find the right dose to fight cancer while reducing a severe side effect: nerve damage that cau…
Matched conditions: PROGNOSTIC STAGE IV BREAST CANCER AJCC V8
Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC
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Genetic testing trial aims to match breast cancer patients with right treatments
Knowledge-focused OngoingThis study is testing whether analyzing the genetic makeup of breast tumors can help predict which standard treatments will work best for individual patients. Researchers are enrolling 1,100 people with early-stage breast cancer to see if genetic testing can accurately identify t…
Matched conditions: PROGNOSTIC STAGE IV BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Mar 19, 2026 14:56 UTC
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Can a simple video unlock better cancer care decisions?
Knowledge-focused OngoingThis study is testing whether a short educational video can help patients with advanced cancer better understand tumor genomic testing. It involves 243 adults with metastatic breast or lung cancer who are already scheduled for this type of testing. Researchers will measure if wat…
Matched conditions: PROGNOSTIC STAGE IV BREAST CANCER AJCC V8
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Mar 10, 2026 12:53 UTC