PROGNOSTIC STAGE IV BREAST CANCER AJCC V8
Clinical trials for PROGNOSTIC STAGE IV BREAST CANCER AJCC V8 explained in plain language.
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Virus injection takes on Hard-to-Treat breast cancer in early trial
Disease control OngoingThis early-phase study tests a new treatment for metastatic triple negative breast cancer, a type that has spread and is hard to treat. The therapy uses a specially designed virus injected directly into tumors to infect and break them down. The main goal is to find the safest dos…
Matched conditions: PROGNOSTIC STAGE IV BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 17, 2026 02:08 UTC
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New drug combo targets BRCA cancers in early trial
Disease control OngoingThis early-phase trial tests a combination of two drugs—niraparib (a PARP inhibitor) and dostarlimab (an immunotherapy)—in people with BRCA-mutated breast, pancreas, or ovarian cancers that have spread or cannot be surgically removed. The goal is to see if the combo can shrink tu…
Matched conditions: PROGNOSTIC STAGE IV BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: University of Washington • Aim: Disease control
Last updated May 17, 2026 02:05 UTC
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New drug shows promise for breast cancer brain tumors
Disease control OngoingThis study tests a drug called sacituzumab govitecan in 44 people with HER2-negative breast cancer that has spread to the brain. The drug works like a smart bomb, attaching to cancer cells and delivering chemotherapy directly to them. The goal is to see if it can shrink brain tum…
Matched conditions: PROGNOSTIC STAGE IV BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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New drug cocktail shows promise against aggressive breast cancer
Disease control OngoingThis study tests a combination of targeted drugs (ribociclib, tucatinib, trastuzumab) for HER2-positive breast cancer that has spread or is in early stages. The goal is to see if these drugs are safe and can shrink tumors before surgery better than standard chemotherapy. About 18…
Matched conditions: PROGNOSTIC STAGE IV BREAST CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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New combo therapy aims to turn tumors against themselves in advanced cancer patients
Disease control OngoingThis early-phase study tests whether a mix of drugs and targeted radiation can help the immune system recognize and attack hard-to-treat solid tumors. About 14 adults with advanced melanoma, breast cancer, or other solid cancers that cannot be surgically removed will receive inje…
Matched conditions: PROGNOSTIC STAGE IV BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: University of Southern California • Aim: Disease control
Last updated May 11, 2026 20:38 UTC
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New scan could improve monitoring of bone metastases in breast cancer
Diagnosis OngoingThis study looks at whether a type of PET/CT scan (FDG-PET/CT) can better measure how breast cancer that has spread to the bones responds to treatment. About 138 adults with hormone receptor-positive, HER2-known breast cancer that is mostly in the bones will get the scan before a…
Matched conditions: PROGNOSTIC STAGE IV BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Diagnosis
Last updated May 14, 2026 12:02 UTC
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Blood test may tame Chemo's nerve damage
Knowledge-focused TerminatedThis study looks at whether doctors can consistently measure the chemotherapy drug paclitaxel in the blood of cancer patients. The goal is to see if this could help adjust doses to kill cancer while reducing nerve damage, a common side effect. About 22 adults with various solid t…
Matched conditions: PROGNOSTIC STAGE IV BREAST CANCER AJCC V8
Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated May 17, 2026 02:07 UTC
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Gene test may guide breast cancer treatment choices
Knowledge-focused OngoingThis study looks at whether testing tumor genes can help predict if HER2-negative breast cancer will respond to chemotherapy or hormone therapy. About 1,100 people with stage I to III breast cancer will have their tumor samples analyzed. The goal is to see if this genetic testing…
Matched conditions: PROGNOSTIC STAGE IV BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated May 17, 2026 02:07 UTC
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Short video boosts cancer Patients' understanding of genetic tests
Knowledge-focused OngoingThis study tests whether watching a short video helps people with metastatic cancer understand tumor genomic testing better. About 243 adults with cancer that has spread will watch the video and answer questions before and after. The goal is to see if the video improves knowledge…
Matched conditions: PROGNOSTIC STAGE IV BREAST CANCER AJCC V8
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated May 05, 2026 11:53 UTC