PRIMARY MEDIASTINAL LARGE B-CELL LYMPHOMA (PMBCL)
Clinical trials for PRIMARY MEDIASTINAL LARGE B-CELL LYMPHOMA (PMBCL) explained in plain language.
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New antibody therapy tested for Tough-to-Treat blood cancers
Disease control OngoingThis trial is testing a new antibody drug called epcoritamab in people with B-cell lymphoma that has come back or stopped responding to standard treatments. The main goals are to find the safest and most effective dose, understand the side effects, and see how well the drug works…
Matched conditions: PRIMARY MEDIASTINAL LARGE B-CELL LYMPHOMA (PMBCL)
Phase: PHASE1, PHASE2 • Sponsor: Genmab • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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New Triple-Target immune cell therapy enters first human trial for tough blood cancers
Disease control ENROLLING_BY_INVITATIONThis is a first-in-human safety study testing a new, experimental CAR-T cell therapy called CAR19.20.22 in adults with B-cell lymphomas that have returned or not responded to at least two prior treatments. The therapy uses the patient's own immune cells, engineered to attack canc…
Matched conditions: PRIMARY MEDIASTINAL LARGE B-CELL LYMPHOMA (PMBCL)
Phase: PHASE1 • Sponsor: University of Maryland, Baltimore • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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Shielding cancer fighters: can a simple vaccine timing trick prevent deadly infections?
Prevention OngoingThis study is testing whether giving a pneumonia vaccine before and after a powerful cancer treatment called CAR T cell therapy can better protect patients from serious infections. It involves 26 adults with certain types of B-cell lymphoma who are scheduled for CAR T therapy. Th…
Matched conditions: PRIMARY MEDIASTINAL LARGE B-CELL LYMPHOMA (PMBCL)
Phase: PHASE2 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Prevention
Last updated Mar 24, 2026 12:02 UTC