PREGNANT WOMEN

This study tests if a medicine called letermovir can better stop the CMV virus in unborn babies than the current standard valaciclovir. Pregnant women who had a first-trimester CMV infection and whose fetus is infected (but without severe brain issues) will receive one of the two…

This study tests a new, ultra-early, non-invasive method to detect fetal chromosomal abnormalities. Researchers will collect cells from the placenta (extravillous trophoblasts) from 25 pregnant women between 7 and 16 weeks of pregnancy. The goal is to see if this method can provi…

This study is testing whether a cream called Stratamark® can prevent stretch marks in pregnant women. 10,000 healthy pregnant women without existing stretch marks on their belly will apply the cream daily and report their results online. The goal is to see if the cream reduces th…

This study compares two easy methods—tapping the skin and applying a cold pack—to see which better reduces pain from tetanus shots in pregnant women. About 90 participants will rate their pain right after the injection and again later. The goal is to find a simple, drug-free way …

This study looks at whether it's safe to avoid placing a bladder catheter during planned cesarean sections. About 550 pregnant women having a planned C-section will be randomly assigned to either get the usual catheter or skip it. The goal is to see if skipping the tube leads to …

This study looks at whether low-risk pregnant women can safely go home after starting labor induction with a balloon catheter, instead of staying in the hospital. About 258 women will be randomly assigned to either go home or stay in the hospital. The goal is to see if going home…

This study looks at how tiny air pollution particles and microplastics might harm fetal development and increase the chance of preterm birth. Researchers will follow 1,600 pregnant women to measure their exposure and track birth outcomes. The goal is to understand the mechanisms …

This study will follow 5,000 pregnant women to see how their heart health affects both them and their babies. Researchers will use a new checklist called "Life's Essential 8" to measure heart health. The goal is to create better heart health standards for pregnancy and improve ou…

This study looks at whether certain substances in the placenta (called sFlt-1 and PlGF) can help doctors know if a baby is in distress during labor. Researchers will monitor 428 pregnant women and compare these markers with standard heart-rate tracings. The goal is to find a bett…

This registry enrolls pregnant women aged 18-45 who take psychiatric medications like antidepressants or ADHD drugs. Researchers will track the health of their babies for the first year of life to see if the medications cause birth defects. The goal is to fill gaps in current saf…