POLYSUBSTANCE ABUSE
Clinical trials for POLYSUBSTANCE ABUSE explained in plain language.
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New study tests mindfulness and motivation to help methadone patients kick multiple habits
Disease control Recruiting nowThis study is testing two counseling approaches—Motivational Interviewing (MI) and Mindfulness-Oriented Recovery Enhancement (MORE)—to help people on methadone treatment reduce their use of tobacco, opioids, and other drugs. Researchers will enroll 420 adults who are currently on…
Matched conditions: POLYSUBSTANCE ABUSE
Phase: PHASE3 • Sponsor: Rutgers, The State University of New Jersey • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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New registry aims to save lives from opioid overdoses in ERs
Knowledge-focused Recruiting nowThis study is building a Canada-wide registry of people who come to emergency departments with opioid poisoning. Researchers will track treatments and outcomes for up to 7,200 patients. The goal is to learn what works best and create a tool to predict who is at highest risk of dy…
Matched conditions: POLYSUBSTANCE ABUSE
Sponsor: University of British Columbia • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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New study aims to uncover why opioid and Anti-Anxiety drug mix is so deadly
Knowledge-focused Recruiting nowThis study is looking at 120 people who are already in treatment for abusing opioids and/or benzodiazepines (anti-anxiety drugs). Researchers want to understand why people use these drugs together, which greatly raises the risk of overdose and death. Participants will complete in…
Matched conditions: POLYSUBSTANCE ABUSE
Sponsor: Wayne State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Small study probes brain effects of mixing opioids and benzodiazepines
Knowledge-focused Recruiting nowThis study is testing how opioids (morphine) and benzodiazepines (alprazolam) affect mood, anxiety, and thinking when taken alone or together. Researchers will give 24 people with a history of using these drugs single doses in a lab and measure their responses. The goal is to und…
Matched conditions: POLYSUBSTANCE ABUSE
Phase: PHASE2 • Sponsor: Wayne State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC