PINEOBLASTOMA
Clinical trials for PINEOBLASTOMA explained in plain language.
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Intensive chemo combo shows promise for kids with aggressive brain cancer
Disease control OngoingThis study tests whether giving three rounds of very strong chemotherapy with stem cell rescue works better than one round for children under 10 with high-risk brain tumors. The goal is to improve survival without adding too many side effects. About 250 children will take part.
Matched conditions: PINEOBLASTOMA
Phase: PHASE4 • Sponsor: Parth Patel • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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New hope for young brain tumor patients: chemotherapy first, then targeted radiation
Disease control OngoingThis clinical trial tests a risk-adapted approach for young children with newly diagnosed brain tumors. The treatment starts with chemotherapy to delay radiation, giving the brain more time to develop. Then, radiation is carefully targeted to the tumor area to reduce side effects…
Matched conditions: PINEOBLASTOMA
Phase: PHASE2 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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Engineered immune cells injected directly into brain show promise for kids with deadly tumors
Disease control OngoingThis early-phase study tests whether specially engineered immune cells (CAR T cells) can be safely given directly into the brain or spinal fluid of children and young adults with HER2-positive brain tumors that have come back or not responded to standard treatments. The therapy a…
Matched conditions: PINEOBLASTOMA
Phase: PHASE1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC