PILONIDAL SINUS

This trial compares two ways to manage the wound after surgical removal of a chronic pilonidal sinus. Half of the 200 participants will receive a negative pressure wound therapy (NPWT) dressing that applies gentle suction to the wound, while the other half will receive standard o…

This trial compares four different surgical techniques for treating pilonidal sinus, a painful skin condition near the tailbone, in adolescents aged 12 to 18. The goal is to find which method causes the least pain, fewest complications, and lowest chance of the sinus coming back.…

This study tests a cream called clascoterone on people with pilonidal disease, a skin condition in the buttock crease. For 12 weeks, participants apply the cream or a placebo twice daily. Researchers check if the cream improves disease severity and symptoms. The trial involves 75…

This study tests a standardized cleft lift operation for people with complex or recurrent pilonidal sinus disease, a painful skin condition near the tailbone. Researchers want to see if this approach leads to faster wound healing and quicker return to daily activities compared to…

This study tests whether an ultrasound-guided nerve block (sacral erector spinae plane block) can reduce pain and the need for strong painkillers after pilonidal sinus surgery. Sixty adults having elective surgery will be randomly assigned to receive either the block plus standar…

This observational study follows 800 adults who receive Myriad™ during soft tissue reconstruction for wounds like abdominal dehiscence, pressure injuries, or anal fistulas. Researchers track healing time, complications, and side effects to understand how well the material works i…

This study follows 240 adults who get laser surgery for pilonidal cysts, a painful skin condition near the tailbone. Researchers will check if the cyst comes back within two years by asking patients questions. The goal is to understand how effective laser treatment is over time.