PHARMACODYNAMICS
Clinical trials for PHARMACODYNAMICS explained in plain language.
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Anesthesia study compares two induction methods to improve brain monitoring accuracy
Knowledge-focused CompletedThis study looked at 70 adults having planned surgery to compare two methods of giving propofol anesthesia: a slow versus a rapid induction. Researchers checked how well each method matched readings from a brain monitor (BIS/Conox). The goal was to see which approach better predi…
Matched conditions: PHARMACODYNAMICS
Sponsor: Pablo O. Sepulveda • Aim: Knowledge-focused
Last updated May 26, 2026 10:22 UTC
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Healthy volunteers test safety of experimental reversal agent
Knowledge-focused CompletedThis early-stage study tested the safety and how the body processes a new drug called BB-025, which is designed to reverse the effects of another drug (BB-031). 72 healthy adults received either BB-025 or a placebo, alone or after BB-031, and were monitored for 28 days. The goal …
Matched conditions: PHARMACODYNAMICS
Phase: PHASE1 • Sponsor: Basking Biosciences, Inc. • Aim: Knowledge-focused
Last updated May 22, 2026 13:54 UTC
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New insulin candidate put to the test against market leader
Knowledge-focused CompletedThis study tested whether a new rapid-acting insulin (I004) works the same as the approved insulin NovoLog. Sixty-nine healthy volunteers received single doses of both insulins in a blinded, crossover design. The goal was to compare how the body absorbs and responds to each insul…
Matched conditions: PHARMACODYNAMICS
Phase: PHASE2, PHASE3 • Sponsor: Amphastar Pharmaceuticals, Inc. • Aim: Knowledge-focused
Last updated May 20, 2026 11:53 UTC
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Kratom under the microscope: new study reveals how it affects the body
Knowledge-focused CompletedThis study looked at how safe kratom is and how the body processes it in healthy adults who have used opioids recreationally. Researchers gave single doses of kratom and monitored side effects and drug levels in the blood. The goal was to gather basic safety and processing inform…
Matched conditions: PHARMACODYNAMICS
Phase: PHASE1 • Sponsor: Altasciences Company Inc. • Aim: Knowledge-focused
Last updated May 19, 2026 11:49 UTC