PEDIATRIC SOLID TUMOR
Clinical trials for PEDIATRIC SOLID TUMOR explained in plain language.
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New drug targets cancer spread in first human trial
Disease control Recruiting nowThis early-phase trial tests a new drug called metarrestin in people with advanced solid tumors that have spread (metastasized). The goal is to find a safe dose and see if it can shrink tumors. The study includes adults with pancreatic, breast, or other solid tumors, and children…
Matched conditions: PEDIATRIC SOLID TUMOR
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Diabetes drug takes on childhood cancers in early safety trial
Disease control Recruiting nowThis early-phase study tests whether dapagliflozin, a diabetes medicine, is safe for children with brain or solid tumors that have come back or not responded to other treatments. About 20 children will receive the drug alongside standard care. The goal is to check for side effect…
Matched conditions: PEDIATRIC SOLID TUMOR
Phase: PHASE1 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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New cocktail of four drugs aims to tackle childhood cancers that Won't go away
Disease control Recruiting nowThis study is testing a combination of four drugs—atezolizumab, sorafenib, bevacizumab, and cyclophosphamide—in children and young adults with solid tumors that have come back or not responded to standard treatment. The goal is to find safe doses and see if the combination can sh…
Matched conditions: PEDIATRIC SOLID TUMOR
Phase: PHASE1, PHASE2 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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Engineered immune cells take aim at childhood cancers
Disease control Recruiting nowThis early-stage trial tests a new immunotherapy for children and young adults up to age 21 with solid tumors that have come back or not responded to standard treatment. The therapy uses the patient's own immune cells, which are modified in a lab to recognize and attack a protein…
Matched conditions: PEDIATRIC SOLID TUMOR
Phase: PHASE1 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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Massive study aims to unlock secrets of rare cancers
Knowledge-focused Recruiting nowThis study is collecting medical information and biological samples from up to 10,000 people with rare solid tumors, their relatives, and those with genetic mutations that raise cancer risk. Researchers hope to learn how these tumors develop and change over time. The goal is to i…
Matched conditions: PEDIATRIC SOLID TUMOR
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Kids' cancer genes mapped in massive study
Knowledge-focused Recruiting nowThis study is collecting and analyzing the complete genetic information (genomes) of up to 2,500 children with cancer. The goal is to learn how gene changes cause different tumors and affect treatment outcomes. This is a non-therapeutic study, meaning it does not test a new treat…
Matched conditions: PEDIATRIC SOLID TUMOR
Sponsor: St. Jude Children's Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Taste and smell tests for kids with cancer: a feasibility study
Knowledge-focused Recruiting nowThis study looks at whether it's possible to measure changes in taste, smell, and eating habits in children aged 7 to 17 who are undergoing cancer treatment. Researchers are testing simple tools like smell and taste tests, saliva measurements, and questionnaires. The goal is to s…
Matched conditions: PEDIATRIC SOLID TUMOR
Phase: NA • Sponsor: Centre Leon Berard • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC
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AI and big data join the fight against childhood brain cancer relapse
Knowledge-focused Recruiting nowThis study looks back at data from 370 children treated for ependymoma, a common brain tumor in kids. Even after surgery and radiation, about half of these tumors return. Researchers are using artificial intelligence to analyze medical images, genetics, and treatment records to f…
Matched conditions: PEDIATRIC SOLID TUMOR
Sponsor: Institut Claudius Regaud • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:02 UTC