PEDIATRIC LOW-GRADE GLIOMA
Clinical trials for PEDIATRIC LOW-GRADE GLIOMA explained in plain language.
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New drug cocktail aims to outsmart childhood brain tumors
Disease control Recruiting nowThis pilot study tests whether combining targeted therapy (MAPK inhibitors like trametinib and dabrafenib) with an immunotherapy drug (nivolumab) can safely and effectively treat children with BRAF-altered gliomas, a type of brain tumor. The study includes children with low-grade…
Matched conditions: PEDIATRIC LOW-GRADE GLIOMA
Phase: PHASE1, PHASE2 • Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago • Aim: Disease control
Last updated Jul 12, 2026 00:00 UTC
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New combo therapy hopes to tackle childhood brain tumors
Disease control Recruiting nowThis study tests a combination of two drugs, mirdametinib (taken by mouth) and vinblastine (given through a vein), in children and young adults with a type of brain tumor called low-grade glioma that has a specific genetic change (MAPK pathway activation). The trial has three par…
Matched conditions: PEDIATRIC LOW-GRADE GLIOMA
Phase: PHASE1, PHASE2 • Sponsor: St. Justine's Hospital • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC