PANCREATIC CARCINOMA

This early-phase study tested a vaccine (p53MVA) plus the drug pembrolizumab in 11 adults with advanced solid tumors that had stopped responding to other treatments. The goal was to see if the combination is safe and can boost the immune system to attack cancer cells. Participant…

This study looks at how safe and effective the diabetes drug glipizide is for lowering blood sugar in people with pancreatic cancer. About 29 adults with active pancreatic cancer and high blood sugar will take glipizide, and their glucose levels will be measured before and after …

This study compares a three-drug chemotherapy combination (nab-paclitaxel, gemcitabine, plus cisplatin) against the standard two-drug combination (nab-paclitaxel plus gemcitabine) for people with metastatic pancreatic cancer that has spread to other parts of the body. Participant…

This study tests whether a pancreatic enzyme replacement called pancrelipase can help maintain or improve body weight in people with metastatic pancreatic cancer. About 17 participants will receive either the enzyme or a placebo, and researchers will measure changes in body mass …

This early-stage study tests a new radioactive tracer called 18F-αvβ6-BP to see if it can safely and effectively image several types of cancer, including breast, colorectal, lung, and pancreatic cancers. About 27 adults with primary or metastatic cancer will receive the tracer an…

This pilot study at Mayo Clinic tests whether personalized education and genetic counseling can increase genetic testing in people who have a first-degree relative with pancreatic cancer. About 40 participants aged 18-75 with a family history but no personal history of the diseas…

This study tests a web-based education tool called HOPE-Genomics that helps cancer patients learn about their genetic test results. About 465 adults with certain cancers (breast, lung, colorectal, and others) will use the tool to see if it improves their understanding of genomics…