OSTEOARTHROSIS
Clinical trials for OSTEOARTHROSIS explained in plain language.
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Nighttime drug cocktail aims to help seniors sleep better after joint surgery
Symptom relief CompletedThis trial tests whether a very low dose of two drugs—dexmedetomidine and esketamine—given at night can improve sleep quality in older adults (65-89 years) undergoing knee or hip replacement. Poor sleep after surgery is common and linked to worse recovery. The study compares the …
Matched conditions: OSTEOARTHROSIS
Phase: PHASE4 • Sponsor: Peking University First Hospital • Aim: Symptom relief
Last updated Jul 08, 2026 00:00 UTC
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Can a Cannabis-Like drug cut opioid use after knee surgery?
Symptom relief CompletedThis study tested whether dronabinol, a drug similar to cannabis, can help reduce the need for opioid painkillers after total knee replacement. 114 adults scheduled for knee surgery were randomly given either dronabinol or a placebo before and after their operation. Researchers m…
Matched conditions: OSTEOARTHROSIS
Phase: PHASE4 • Sponsor: Hospital for Special Surgery, New York • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC