OSTEOARTHRITIS (OA)
Clinical trials for OSTEOARTHRITIS (OA) explained in plain language.
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Robot vs surgeon: which knee replacement works better?
Symptom relief Not yet recruitingThis study compares two types of total knee replacement surgery for people with knee osteoarthritis: one done manually and one assisted by a robotic device (VELYS). About 346 participants will be randomly assigned to one of the two surgeries and followed for a year to see which l…
Matched conditions: OSTEOARTHRITIS (OA)
Phase: NA • Sponsor: Golden Jubilee National Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Can a single online class ease severe arthritis pain?
Symptom relief Not yet recruitingThis study tests a 2-hour online class called Empowered Relief for 100 adults with advanced knee or hip osteoarthritis who cannot have joint replacement surgery. The class teaches simple pain management skills based on cognitive behavioral therapy and mindfulness. Researchers wil…
Matched conditions: OSTEOARTHRITIS (OA)
Phase: NA • Sponsor: Cedars-Sinai Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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New painkiller could cut opioid use after knee surgery
Symptom relief Not yet recruitingThis study tests whether a long-acting painkiller (bupivacaine-meloxicam) can reduce pain and the need for opioid medications after robot-assisted knee replacement. 150 adults with knee osteoarthritis will receive either the new painkiller or a standard injection. Researchers wil…
Matched conditions: OSTEOARTHRITIS (OA)
Phase: PHASE4 • Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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Could a fluid from stem cells ease knee pain without surgery?
Symptom relief Not yet recruitingThis early-phase trial tests whether injecting a fluid made from stem cells (called secretome) mixed with growth factors from the patient's own blood can safely reduce knee pain and improve function in people with mild knee osteoarthritis. The study will enroll 25 adults aged 30-…
Matched conditions: OSTEOARTHRITIS (OA)
Phase: EARLY_PHASE1 • Sponsor: University of the Punjab • Aim: Symptom relief
Last updated Jun 26, 2026 13:45 UTC
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Can weak muscles slow down hip surgery recovery? new study aims to find out
Knowledge-focused Not yet recruitingThis study at Montpellier University Hospital will look at whether low muscle mass and strength before hip replacement surgery affects how well people aged 75 and older regain their independence. About 20 volunteers will have blood tests, scans, and a tiny muscle sample taken dur…
Matched conditions: OSTEOARTHRITIS (OA)
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC