ORAL CAVITY CARCINOMA
Clinical trials for ORAL CAVITY CARCINOMA explained in plain language.
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Could skipping the flap during radiation reduce side effects without harming cancer control?
Disease control Recruiting nowThis study tests whether avoiding radiation to the surgical flap (the tissue used to rebuild the mouth after cancer removal) is as effective as standard radiation that treats the whole area. About 348 adults with oral cavity cancer who had reconstructive surgery will be randomly …
Matched conditions: ORAL CAVITY CARCINOMA
Phase: PHASE3 • Sponsor: Centre Francois Baclesse • Aim: Disease control
Last updated Jul 24, 2026 00:00 UTC
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New injection fights head and neck cancer from the inside
Disease control Recruiting nowThis early-stage trial tests a new treatment called VLPONC-01, which is injected directly into head and neck tumors. It delivers a substance (IL-12) that may help the immune system attack the cancer. Some participants will also receive the immunotherapy drug pembrolizumab. The ma…
Matched conditions: ORAL CAVITY CARCINOMA
Phase: PHASE1 • Sponsor: VLP Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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3D-Printed mouth guards could ease radiation side effects for cancer patients
Symptom relief Recruiting nowThis study tests whether custom 3D-printed oral stents can reduce mouth sores in head and neck cancer patients receiving radiation therapy. The stents are made from a mold of the patient's mouth and cover teeth and gums during treatment. Researchers will compare sore rates and pa…
Matched conditions: ORAL CAVITY CARCINOMA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:08 UTC
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Can a single drink reveal how alcohol triggers oral cancer?
Knowledge-focused Recruiting nowThis study investigates how acetaldehyde, a byproduct of alcohol, affects cells in the mouth and whether it may increase oral cancer risk. Healthy volunteers and individuals with Fanconi anemia (a condition linked to higher cancer risk) will consume a single dose of alcohol and p…
Matched conditions: ORAL CAVITY CARCINOMA
Phase: NA • Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Knowledge-focused
Last updated Jul 24, 2026 00:00 UTC