OPEN TIBIA FRACTURE
Clinical trials for OPEN TIBIA FRACTURE explained in plain language.
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Speed saves limbs: trial tests 72-Hour flap surgery for crushed legs
Disease control Recruiting nowThis study compares getting flap surgery within 72 hours of a severe leg injury versus waiting longer. The goal is to see if faster surgery reduces death, amputation, infections, and hospital stays. About 356 adults with open fractures or dislocations below the knee will take par…
Matched conditions: OPEN TIBIA FRACTURE
Phase: NA • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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New Antibiotic-Coated nail aims to stop bone infections after severe leg breaks
Prevention Recruiting nowThis study tests whether coating a metal rod (intramedullary nail) with antibiotics (vancomycin and gentamicin) can prevent deep infections in people with severe open tibia fractures. About 484 adults with Gustilo Type II or III open tibia fractures will be randomly assigned to r…
Matched conditions: OPEN TIBIA FRACTURE
Phase: PHASE4 • Sponsor: Wake Forest University Health Sciences • Aim: Prevention
Last updated Jun 27, 2026 12:37 UTC