NEUROMUSCULAR DISEASES

This study continued testing an experimental drug called AOC 1001 in adults with myotonic dystrophy type 1, a genetic muscle-wasting disease. It followed 37 participants from a previous trial to check long-term safety and see if the drug continues to work when given every 8 weeks…

This completed Phase 3 trial tested whether adding the experimental drug apitegromab to standard SMA treatments could improve muscle function in 188 children and young adults (ages 2-21) with later-onset spinal muscular atrophy. All participants were already receiving approved SM…

This study tested whether a drug called ataluren could slow the progression of muscle weakness in boys with a specific genetic form of Duchenne muscular dystrophy. For 72 weeks, 360 participants received either ataluren or a placebo, followed by another 72 weeks where everyone re…

This study tested whether a special suit that delivers mild electrical stimulation could help people with fibromyalgia. Twenty-eight participants wore either an active or inactive version of the suit for two weeks to see if it reduced pain, fatigue, and improved their quality of …

This study aimed to understand why football players often re-injure their hamstrings. Researchers measured muscle activity in 42 male players, comparing those with a past hamstring injury to healthy players. They found that even after recovery, injured players showed weaker activ…

This study aimed to understand how muscles use oxygen during exercise in people with different neuromuscular diseases, compared to healthy people. Seventeen participants performed a leg exercise while researchers measured oxygen levels in their muscles using a special light-based…