NEURO-DEGENERATIVE DISEASE

This study tests a drug called cobimetinib in children and adults with histiocytic disorders that have come back or not responded to other treatments. Cobimetinib blocks a faulty growth signal inside cells. The goal is to see if the drug can shrink tumors and slow the disease. Ab…

This study tests whether lightweight, 3D-printed cutlery handles customized to each patient's hand can help elderly people with neurodegenerative diseases eat more independently. About 75 hospitalized patients will try handles of different sizes, and researchers will measure chan…

This study looks at the experiences of extended family members—like grandchildren, siblings, and nieces/nephews—who care for a loved one with dementia. Researchers will interview 240 caregivers about their daily tasks, stress, and the support they use. The goal is to find ways to…

This study is looking at whether simple, non-invasive eye scans can help detect and track brain diseases like Alzheimer's, Parkinson's, and multiple sclerosis. Researchers will use special cameras to take detailed pictures of the retina in 2,000 adults—both those with and without…

This study follows 20 people with a rare nerve disease called CMT4J to learn how the condition progresses. Participants of any age will be checked once a year for two years. The goal is to better understand the disease, not to test a treatment.