NEPHROTIC SYNDROME IN CHILDREN

This study tests a noninvasive device that stimulates a nerve in the ear to help children with steroid-resistant nephrotic syndrome, a kidney condition that doesn't respond to standard steroids. The device aims to calm the immune system and reduce inflammation, potentially allowi…

This study tests if dupilumab can help children with severe nephrotic syndrome stay relapse-free longer. About 66 kids aged 6-18 will receive either dupilumab or a placebo injection every 2-4 weeks for 6 months, while slowly reducing their steroid dose. The goal is to see if dupi…

This study tests a new drug called SG301, given as a shot under the skin, for children aged 6 to 18 who have nephrotic syndrome that keeps coming back or requires steroids to stay in remission. The goal is to see if it can safely reduce relapses and help children stay off steroid…

This small pilot study is testing whether a gentle, non-invasive nerve stimulation device worn on the ear can help children with a frequently relapsing kidney disease. The goal is to see if this approach can reduce disease flare-ups and the need for strong steroid medications. Re…

This study helps people with certain kidney diseases (like nephrotic syndrome and FSGS) find clinical trials that might be a good fit for their specific condition. Researchers use advanced molecular testing to match each person's unique disease profile to targeted therapies being…

This study interviews 150 children, adults, and parents about their experiences with swelling caused by Nephrotic Syndrome. Researchers will use the information to create a survey that helps test new medications. No treatment is given; the goal is to better understand symptoms.