MYELOMA

This study followed 419 adults newly diagnosed with multiple myeloma, a blood cancer, to see how well a specific three-drug combination (VRD) works in real-world hospital practice. Patients received the drug regimen, and those eligible also underwent a stem cell transplant, follo…

This early-stage study aimed to find a safe dose of a new drug combination (BMS-986345 plus duvelisib) for patients with advanced blood cancers like lymphoma and leukemia. It involved 14 adults whose cancers had progressed after other treatments. The main goal was to check for si…

This early-stage study tested a new, lab-made cell therapy called FT576 in patients with multiple myeloma that had returned or stopped responding to standard treatments. The main goals were to find a safe dose and see if the treatment, given alone or with an existing drug (daratu…

This study tested a new drug called Elranatamab for Chinese patients with a severe form of multiple myeloma that no longer responds to standard treatments. The drug is an injection that works by activating the body's own immune system to attack the cancer cells. The trial had two…

This small, early study tested if breathing pure oxygen in a pressurized chamber could help people with multiple myeloma recover faster from a stem cell transplant. The main goal was to see if adding this oxygen therapy was safe and didn't cause serious side effects. Researchers …

This study tested a two-step transplant approach for patients under 65 with aggressive myeloma. After an initial transplant, patients who had a partial response received a second, gentler transplant from a donor. The goal was to better control the disease and improve survival by …

This small, early-stage study tested whether temporarily removing a specific type of immune cell, called a regulatory T cell, during a patient's own stem cell transplant could be done safely for people with multiple myeloma. The goal was to see if this change might help the immun…

This study tested whether easier methods—a simple blood draw and a full-body MRI scan—could accurately track tiny amounts of remaining cancer in people with multiple myeloma. It involved 36 adults with the disease, comparing these new methods against the current painful standard,…

This study tested if paying for blood transfusions would help people with advanced blood cancers choose hospice care earlier. Patients often delay hospice because they need transfusions, which hospice usually doesn't cover. The research provided free transfusions to see if this h…

This study aimed to understand how well the Pfizer COVID-19 vaccine works in adults with weakened immune systems compared to healthy adults. Researchers measured antibody levels in the blood and nose of 196 participants, including people with conditions like cancer, HIV, and orga…