MYELOFIBROSIS (MF)
Clinical trials for MYELOFIBROSIS (MF) explained in plain language.
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New pill tested for rare blood cancers
Disease control Recruiting nowThis is a first-in-human study to test the safety and find the right dose of an experimental oral drug called PRT12396 for people with certain rare blood cancers. It will enroll about 100 adults with high-risk polycythemia vera or myelofibrosis. The main goal is to see how well t…
Matched conditions: MYELOFIBROSIS (MF)
Phase: PHASE1 • Sponsor: Prelude Therapeutics • Aim: Disease control
Last updated Apr 01, 2026 20:26 UTC
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New hope for myelofibrosis patients who stopped responding to standard treatment
Disease control Recruiting nowThis early-stage study is testing whether adding a new drug called roginolisib to the standard treatment ruxolitinib is safe and tolerable for adults with myelofibrosis, a serious bone marrow cancer. It aims to help patients whose disease has not responded well to ruxolitinib alo…
Matched conditions: MYELOFIBROSIS (MF)
Phase: PHASE1, PHASE2 • Sponsor: iOnctura • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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New hope for rare blood cancers: testing a powerful drug duo
Disease control Recruiting nowThis study is testing a new two-drug combination for adults with two rare and serious blood cancers: myelofibrosis (MF) and chronic myelomonocytic leukemia (CMML). The main goals are to find the safest and most effective dose of the new drug axatilimab, both alone and when added …
Matched conditions: MYELOFIBROSIS (MF)
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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Old arthritis drug could offer new hope for rare blood cancers
Disease control Recruiting nowThis study is testing whether adding a low-dose, inexpensive drug called methotrexate helps people with certain rare blood cancers. Researchers want to see if it safely reduces symptoms like enlarged spleen, fatigue, and abnormal blood cell counts when added to a patient's curren…
Matched conditions: MYELOFIBROSIS (MF)
Phase: PHASE2 • Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Disease control
Last updated Mar 19, 2026 14:56 UTC
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New test could replace painful bone marrow biopsies for blood cancer patients
Diagnosis Recruiting nowThis study is testing new, less invasive ways to track scarring (fibrosis) in the bone marrow of people with myelofibrosis, a serious blood disorder. Researchers want to see if a simple blood test or a special PET scan can accurately measure this scarring, which currently require…
Matched conditions: MYELOFIBROSIS (MF)
Phase: NA • Sponsor: Azienda Ospedaliero-Universitaria di Parma • Aim: Diagnosis
Last updated Mar 31, 2026 12:12 UTC
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Massive 5,000-Person study launches to map the journey of rare blood cancers
Knowledge-focused Recruiting nowThis is a long-term observational study aiming to better understand a group of rare, chronic blood cancers called myeloproliferative neoplasms (MPNs). It will follow 5,000 adults in the U.S. who have been diagnosed with an MPN for at least five years, collecting information from …
Matched conditions: MYELOFIBROSIS (MF)
Sponsor: MPN Research Foundation • Aim: Knowledge-focused
Last updated Mar 18, 2026 14:40 UTC