MYELOFIBROSIS，MF
Clinical trials for MYELOFIBROSIS，MF explained in plain language.
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Head-to-Head trial aims to find best drug for tough blood cancer
Disease control Not yet recruitingThis study directly compares two already-approved drugs, momelotinib and ruxolitinib, for people newly diagnosed with myelofibrosis who also have low blood cell counts. The main goal is to see which drug is better at shrinking an enlarged spleen and reducing the need for blood tr…
Matched conditions: MYELOFIBROSIS，MF
Phase: PHASE4 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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New hope for scarred bone marrow: drug trial aims to make transplants safer
Disease control Not yet recruitingThis study is testing whether adding the drug Gecacitinib before, during, and after a stem cell transplant can help people with myelofibrosis, a serious bone marrow disease. The main goal is to see if the drug helps patients survive the first year after transplant without their d…
Matched conditions: MYELOFIBROSIS，MF
Phase: PHASE2 • Sponsor: Institute of Hematology & Blood Diseases Hospital, China • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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New hope for scarred bone marrow? drug trial targets tough blood cancer complication
Disease control Not yet recruitingThis study is testing if the drug pacritinib can reduce harmful scarring (fibrosis) in the bone marrow of patients with myelofibrosis, a type of blood cancer, who also have low platelet counts. It will involve about 30 patients who will take the drug for up to two years. Research…
Matched conditions: MYELOFIBROSIS，MF
Phase: PHASE2 • Sponsor: Grupo Español de Enfermedades Mieloproliferativas Crónicas PH Negativas • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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New drug study aims to shrink enlarged spleens in blood disorder patients
Disease control Not yet recruitingThis study observes how well the drug momelotinib works for people with myelofibrosis, a serious bone marrow disorder, in real-world medical settings. Researchers will follow 93 adult patients who have an enlarged spleen to see if the treatment reduces spleen size by at least hal…
Matched conditions: MYELOFIBROSIS，MF
Sponsor: Gruppo Italiano Malattie EMatologiche dell'Adulto • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Stanford tests bold move: stop rejection drug early after transplant
Disease control Not yet recruitingThis study aims to see if it's safe and possible to stop a key anti-rejection medication (tacrolimus) much earlier than usual after a bone marrow transplant. It will involve 50 adults with various blood cancers who receive a transplant from a matched donor. The goal is to reduce …
Matched conditions: MYELOFIBROSIS，MF
Phase: PHASE1 • Sponsor: Stanford University • Aim: Disease control
Last updated Mar 06, 2026 15:37 UTC