MUSCULOSKELETAL INJURY
Clinical trials for MUSCULOSKELETAL INJURY explained in plain language.
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New brace and rehab combo aims to get people with leg injuries back on their feet
Disease control Recruiting nowThis study is testing whether a custom energy-storing leg brace, combined with a high-intensity rehabilitation program, can improve walking, stair climbing, and daily function in people with lower leg injuries. About 370 adults who have been fitted with the brace will be followed…
Matched conditions: MUSCULOSKELETAL INJURY
Sponsor: Wake Forest University Health Sciences • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Feelings as medicine: new therapy targets pain after broken bones
Symptom relief Recruiting nowThis study tests a type of talk therapy called Emotional Awareness and Expression Therapy (EAET) for people who have ongoing pain after a serious orthopedic injury. Researchers want to see if it's possible to run a larger study by checking how many people sign up, attend sessions…
Matched conditions: MUSCULOSKELETAL INJURY
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Could a simple gel replace pills for Kids' pain?
Symptom relief Recruiting nowThis pilot study tests whether a topical diclofenac gel (Voltaren) works as well as oral ibuprofen for reducing pain in children aged 6-18 with ankle or knee sprains. Sixty participants will use either the gel or oral medicine three times a day for three days, then report their p…
Matched conditions: MUSCULOSKELETAL INJURY
Phase: PHASE3 • Sponsor: University of Calgary • Aim: Symptom relief
Last updated Jun 27, 2026 12:06 UTC
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Antidepressant may ease pain and PTSD after trauma
Symptom relief Recruiting nowThis study tests whether giving fluoxetine (Prozac) immediately after a serious injury can prevent depression, PTSD, and reduce pain and opioid use. About 200 adults with fractures or other bodily trauma will receive either fluoxetine or a placebo during their hospital stay. The …
Matched conditions: MUSCULOSKELETAL INJURY
Phase: PHASE4 • Sponsor: University of Florida • Aim: Symptom relief
Last updated Jun 27, 2026 12:06 UTC
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5,000 athletes to help unlock secrets of ACL injuries
Knowledge-focused Recruiting nowThis observational study will collect movement data from 5,000 healthy athletes aged 10 to 65 who play organized sports. Researchers will track participants for 12 months to see who gets injured, especially ACL tears. The goal is to build a database of normal movement patterns to…
Matched conditions: MUSCULOSKELETAL INJURY
Sponsor: Sanford Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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Concussion may raise risk of muscle injuries – study seeks answers
Knowledge-focused Recruiting nowThis study aims to understand how a concussion changes the way people move, which may increase their risk of muscle and bone injuries. Researchers will compare movement patterns in 148 military members who have had a concussion with those who have not. The goal is to find specifi…
Matched conditions: MUSCULOSKELETAL INJURY
Sponsor: Walter Reed National Military Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Braces get a Tune-Up: study tests best heel cushion for easier walking
Knowledge-focused Recruiting nowThis study looks at how changing the heel cushion on an ankle-foot brace (AFO) affects walking in people who use one daily. Forty adults with leg injuries or nerve problems will try four different heel wedges—tall or short, soft or firm—while walking at controlled speeds. Researc…
Matched conditions: MUSCULOSKELETAL INJURY
Phase: NA • Sponsor: University of Iowa • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC