MUSCLE-INVASIVE BLADDER CARCINOMA
Clinical trials for MUSCLE-INVASIVE BLADDER CARCINOMA explained in plain language.
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Bladder cancer drug combo trial halted before enrolling a single patient
Disease control TerminatedThis study aimed to test two treatments for muscle-invasive bladder cancer in patients who cannot receive the standard chemotherapy drug cisplatin. The treatments were erdafitinib (a targeted pill) alone or combined with atezolizumab (an immunotherapy). The goal was to see if the…
Matched conditions: MUSCLE-INVASIVE BLADDER CARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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New hope: immune drug may let some bladder cancer patients avoid bladder removal
Disease control OngoingThis study tests whether the immunotherapy drug pembrolizumab can shrink muscle-invasive bladder cancer enough to allow some patients to keep their bladder. About 46 adults with localized cancer will receive pembrolizumab, then be rechecked. If the cancer is gone or nearly gone, …
Matched conditions: MUSCLE-INVASIVE BLADDER CARCINOMA
Phase: PHASE2 • Sponsor: Matthew Galsky • Aim: Disease control
Last updated May 15, 2026 11:53 UTC
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New hope for bladder cancer: chemo, immunotherapy, and radiation may save the bladder
Disease control OngoingThis study tests a treatment plan for muscle-invasive bladder cancer that aims to avoid bladder removal. About 71 participants will receive chemotherapy and an immunotherapy drug (toripalimab) before radiation therapy, plus more immunotherapy during radiation. The goal is to see …
Matched conditions: MUSCLE-INVASIVE BLADDER CARCINOMA
Phase: PHASE2 • Sponsor: Sun Yat-sen University • Aim: Disease control
Last updated May 11, 2026 20:38 UTC
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Immunotherapy boost may help bladder cancer patients avoid surgery
Disease control OngoingThis study tests whether adding the immunotherapy drug atezolizumab to standard chemoradiation helps people with muscle-invasive bladder cancer live longer without their cancer returning. About 475 adults with localized disease that hasn't spread are taking part. The goal is to s…
Matched conditions: MUSCLE-INVASIVE BLADDER CARCINOMA
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 26, 2026 19:37 UTC
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New radiation method aims to cut bowel problems in bladder cancer patients
Symptom relief OngoingThis study tests a daily adaptive radiation therapy for muscle-invasive bladder cancer. The goal is to see if this personalized approach reduces diarrhea and other bowel side effects compared to standard radiation. About 110 adults with bladder cancer will participate, and the tr…
Matched conditions: MUSCLE-INVASIVE BLADDER CARCINOMA
Phase: NA • Sponsor: Varian, a Siemens Healthineers Company • Aim: Symptom relief
Last updated May 15, 2026 11:56 UTC