MPNST
Clinical trials for MPNST explained in plain language.
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New drug targets rare nerve tumors in people with specific gene loss
Disease control Recruiting nowThis study tests an experimental drug called BMS-986504 in people with a rare cancer called malignant peripheral nerve sheath tumor (MPNST) that cannot be removed by surgery. Only people whose tumors are missing a gene called MTAP can join. The drug is taken daily by mouth, and t…
Matched conditions: MPNST
Phase: PHASE1, PHASE2 • Sponsor: Ankit Mangla, MD • Aim: Disease control
Last updated Aug 13, 2026 00:00 UTC
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Could a cancer drug that blocks a key protein help kids with relapsed wilms tumor?
Disease control Recruiting nowThis phase II trial is testing the drug selinexor in people with Wilms tumor, rhabdoid tumor, MPNST, or other solid tumors that have returned or not responded to treatment. Selinexor works by blocking a protein called XPO1, which is often overactive in these cancers. The study ai…
Matched conditions: MPNST
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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Pen-Like device could help surgeons detect cancer in real time
Diagnosis Recruiting nowThis study tests whether a handheld device called the MasSpec Pen can tell the difference between cancerous MPNST, benign neurofibromas, and normal tissue during surgery. About 60 people with MPNST or neurofibroma will take part. The goal is to see if the device is safe and accur…
Matched conditions: MPNST
Sponsor: M.D. Anderson Cancer Center • Aim: Diagnosis
Last updated Jun 27, 2026 12:05 UTC