MPNST
Clinical trials for MPNST explained in plain language.
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New drug targets rare nerve tumors in people with specific gene loss
Disease control Not yet recruitingThis study tests an experimental drug called BMS-986504 in people with a rare cancer called malignant peripheral nerve sheath tumor (MPNST) that cannot be removed by surgery. Only people whose tumors are missing a gene called MTAP can join. The drug is taken daily by mouth, and t…
Matched conditions: MPNST
Phase: PHASE1, PHASE2 • Sponsor: Ankit Mangla, MD • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New drug cocktail takes on rare nerve tumors
Disease control Not yet recruitingThis early-phase trial tests a combination of three drugs—selumetinib, ZEN-3694, and durvalumab—in people with advanced sarcomas, including malignant peripheral nerve sheath tumors (MPNST) linked to NF1. The study first checks safety and dosing, then looks at whether the treatmen…
Matched conditions: MPNST
Phase: PHASE2 • Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC