MONOGENIC OBESITY
Clinical trials for MONOGENIC OBESITY explained in plain language.
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Could a popular Weight-Loss drug help people with rare genetic obesity?
Disease control Recruiting nowThis study follows 175 adolescents and adults with monogenic obesity—a rare form caused by specific gene changes—who are taking semaglutide (Ozempic/Wegovy). Researchers will track weight and BMI changes over 4 years to see if the drug helps control weight in this group. The goal…
Matched conditions: MONOGENIC OBESITY
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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New drug hopes to curb rare genetic obesity
Disease control Recruiting nowThis study tests an experimental drug called mibavademab in people with a rare form of obesity caused by a faulty leptin gene. The drug aims to help control hunger and body weight. Only 4 participants will be enrolled to see how well it works and if it is safe.
Matched conditions: MONOGENIC OBESITY
Phase: PHASE3 • Sponsor: Regeneron Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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New hope for teens with rare obesity: weekly shot shows promise
Disease control Recruiting nowThis study looks at whether a once-weekly injection of semaglutide (2.4 mg) can help teenagers with monogenic obesity lose weight and feel better. About 70 teens aged 12 to 20 will take the drug along with diet and exercise changes for 68 weeks. The main goal is to see if at leas…
Matched conditions: MONOGENIC OBESITY
Sponsor: Prof. Dr. Martin Wabitsch • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC