Weekly shot helps teens with rare obesity lose weight

NCT ID NCT07302802

First seen Jan 07, 2026 · Last updated May 23, 2026 · Updated 28 times

Summary

This study looks at whether a once-weekly injection of semaglutide, along with diet and exercise, helps teenagers with monogenic obesity lose weight. About 70 teens aged 12 to 20 will take part for 68 weeks. The main goal is to see if at least 10% of their body mass index (BMI) is reduced.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Assistance Publique-Hôpitaux de Paris (AP-HP), Trousseau Hospital Paris, Pediatric Nutrition Department

    NOT_YET_RECRUITING

    Paris, France

    Contact Email: •••••@•••••

  • Departments of Pediatrics & Pediatric Endocrinology, Hospital Infantil Universitario Niño Jesús, Universidad Autónoma de Madrid

    NOT_YET_RECRUITING

    Madrid, 28009, Spain

    Contact Email: •••••@•••••

  • Division of Paediatric Endocrinology and Diabetes, Department of Paediatrics and Adolescent Medicine, Ulm University Medical Centre

    RECRUITING

    Ulm, 89075, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institute for Experimental Pediatric Endocrinology, Charité Universitätsmedizin Berlin

    NOT_YET_RECRUITING

    Berlin, 13353, Germany

    Contact Email: •••••@•••••

  • University Hospital for Children and Adolescents, Center for Pediatric Research, Medical Faculty, University of Leipzig

    NOT_YET_RECRUITING

    Leipzig, 04103, Germany

    Contact Email: •••••@•••••

  • University Medical Center Rotterdam, Erasmus MC-Sophia Children's Hospital

    NOT_YET_RECRUITING

    Rotterdam, 3015 GD, Netherlands

    Contact Email: •••••@•••••

  • Wellcome-MRC Institute of Metabolic Science and NIHR Cambridge Biomedical Research Centre

    NOT_YET_RECRUITING

    Cambridge, CB2 0QQ, United Kingdom

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.