MICROBIOME DYSBIOSIS

This study tests whether giving a probiotic (Infloran®) to infants who received antibiotics in their first month of life can improve their immune response to routine vaccines. Antibiotics can reduce helpful gut bacteria, which may weaken vaccine protection. The trial will compare…

This study tests whether a daily oral synbiotic (a mix of probiotics and prebiotics) can help women with a history of preterm birth carry their baby longer. About 400 pregnant women will take either the supplement or a placebo from early pregnancy. The goal is to see if the suppl…

After brain surgery, many patients need a breathing machine in the ICU. This study will follow 220 such patients to see how the natural bacteria in their lungs change over time. Researchers will collect airway samples and use advanced lab tests to link those changes to the risk o…

This study tests whether a colon-targeted form of vitamin B2 (riboflavin) can improve gut bacteria and digestive health better than regular vitamin B2 or a placebo. Researchers will enroll 90 healthy adults aged 50-70 to compare effects over 56 days. The goal is to understand how…

This study follows 600 burn patients and 60 healthy people over two years to see how burns change the community of microbes on the skin and in the gut. Researchers will collect swabs, stool, and blood samples at several time points to map these changes. The goal is to better unde…