METASTATIC SOLID TUMORS
Clinical trials for METASTATIC SOLID TUMORS explained in plain language.
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New drug duo aims to reboot immune attack on Hard-to-Treat cancers
Disease control CompletedThis early-phase trial tested a new drug called M6223, which blocks a protein called TIGIT that can turn off immune cells. M6223 was given alone or together with another drug, bintrafusp alfa, to 58 people with advanced solid tumors that had stopped responding to standard treatme…
Matched conditions: METASTATIC SOLID TUMORS
Phase: PHASE1 • Sponsor: EMD Serono Research & Development Institute, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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New combo therapy shows promise for Hard-to-Treat cancers
Disease control CompletedThis study tested a new immunotherapy drug, ezabenlimab, combined with other cancer medicines in 211 adults with advanced solid tumors that had spread. The goal was to see if the tumors shrank or disappeared. Participants received different drug combinations, and doctors monitore…
Matched conditions: METASTATIC SOLID TUMORS
Phase: PHASE2 • Sponsor: Boehringer Ingelheim • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Immune cocktail shows promise in early trial for stubborn cancers
Disease control CompletedThis early-phase study tested a new mix of three drugs—IL-15, nivolumab, and ipilimumab—in 31 adults with cancers that no longer respond to standard treatments. The goal was to find the safest dose and see if the combination could help the immune system attack tumors. Participant…
Matched conditions: METASTATIC SOLID TUMORS
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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Cancer drug Trodelvy's Long-Term safety checked in small study
Disease control CompletedThis study looked at the long-term safety of the drug sacituzumab govitecan (Trodelvy) in 25 people with metastatic solid tumors who were already benefiting from the treatment. Participants continued to receive the drug intravenously, and researchers tracked any side effects or l…
Matched conditions: METASTATIC SOLID TUMORS
Phase: PHASE4 • Sponsor: Gilead Sciences • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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Massive tumor study counts rare gene fusions
Knowledge-focused CompletedThis completed study examined tumor samples from 3820 people with advanced solid tumors to find how many have NTRK gene fusions. Researchers used genetic testing to identify these rare changes. The study did not test any treatment, but aims to guide future targeted therapy decisi…
Matched conditions: METASTATIC SOLID TUMORS
Sponsor: Institut Bergonié • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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New study reveals key factors in 90-Day survival for advanced cancer patients after ER
Knowledge-focused CompletedThis completed study reviewed medical records of 1,250 advanced cancer patients who visited the emergency department. Researchers looked at factors like age, tumor type, and blood test results to see which patients were at higher risk of dying within 90 days. The goal is to help …
Matched conditions: METASTATIC SOLID TUMORS
Sponsor: Ankara Etlik City Hospital • Aim: Knowledge-focused
Last updated Jun 26, 2026 16:47 UTC