MENINGIOMA

This study tests a drug called zanzalintinib in 100 people with meningioma (a type of brain tumor) that has returned or grown despite standard treatments like surgery or radiation. The goal is to see if the drug can shrink tumors or slow their growth. Participants take the drug b…

This study tests a new approach for people with brain tumors that have not responded to standard treatments. A lab test called pharmacoscopy analyzes a patient's tumor cells to find which drugs might work best for them. The goal is to see if this personalized method is feasible a…

This study tests an experimental drug called JZP3507 in 30 adults with recurrent grade 2 or 3 meningioma, a type of brain tumor. Participants take the drug orally to see if it can shrink or control the tumor. The goal is to find a new treatment option for people who have not resp…

This early-stage study tests a fluorescent dye called panitumumab-IRDye800 to see if it can help surgeons identify brain tumors during surgery. About 30 adults with brain lesions (like meningioma or glioblastoma) will receive the dye before their operation. The main goal is to ch…

This study tests whether dexmedetomidine, a sedative and painkiller, can lower pain and prevent confusion (delirium) after brain surgery. Sixty adults having elective brain tumor removal will receive either the drug or a placebo. The goal is to improve recovery and reduce the nee…

This study tests a French questionnaire designed to measure quality of life in adults with meningioma, a type of brain tumor. About 238 participants will fill out online surveys about their well-being. No treatment or extra visits are involved. The goal is to make sure the questi…

This study will use a special PET scan to look for a protein called PSMA in people whose meningioma brain tumors have come back after standard treatments. The goal is to see how many of these tumors have enough PSMA to possibly be treated with a new type of targeted radiation the…

This study will compare two types of PET scans (Ga-68-DOTATATE and Ga-68-DOTATOC) in 6 adults with suspected meningioma who are scheduled for surgery. The goal is to see which scan gives clearer images of the tumor. Results may help doctors choose the best imaging method for futu…

This study aims to find out if tumor cells can be detected in the blood or spinal fluid of 15 patients whose aggressive meningiomas have come back after treatment. By looking for these cells, researchers hope to better understand how these tumors spread and recur. The study does …

This study looks at how things like race, income, education, and life history may affect the health of people with meningioma, the most common type of brain tumor. Researchers will gather information from 3,000 adults to find patterns that could explain why some groups have worse…