MENINGIOMA

This study is testing a personalized approach to find treatments for brain tumors that have stopped responding to standard therapies. Doctors will test tumor cells from surgery in a lab to see which drugs might work best for each patient. The goal is to see if this 'drug-matching…

This study is testing whether an experimental drug called zanzalintinib can help control recurrent meningioma brain tumors that have continued growing despite standard treatments like surgery and radiation. The trial will enroll 100 adults whose tumors have returned or progressed…

This early study is testing a special fluorescent dye called panitumumab-IRDye800. It is given by IV before brain surgery to see if it makes tumors glow under a special camera, helping surgeons see the edges of the tumor more clearly. The main goals are to check if the dye is saf…

This study aims to compare two similar types of PET scans used to image a specific kind of brain tumor called a meningioma. It will enroll 6 adult patients who are already scheduled for surgery to see if one scan method works as well as the other. The goal is to gather informatio…

This study aims to find the best way to close the skin after brain tumor surgery. Researchers will compare two common stitching techniques in 382 adult patients to see which leads to fewer wound problems like infections or leaks. The goal is to improve healing so patients can rec…

This study aims to see if a drug called dexmedetomidine can help patients feel less pain and be less confused after brain surgery. It will involve 60 adults having planned brain surgery. Researchers will compare the drug to a placebo to see if it lowers pain scores, reduces the n…

This study aims to test a new French questionnaire designed to measure how a specific type of brain tumor, called a meningioma, affects a person's quality of life. About 238 adults diagnosed with this tumor will be asked to fill out online surveys about their health and daily exp…

This study aims to see if cancer cells from aggressive, recurring brain tumors (meningiomas) can be found in a patient's blood or spinal fluid. Researchers will test samples from 15 adults whose tumors have come back after surgery. The goal is to learn if these 'liquid biopsies' …

This study aims to understand how social factors and personal risks affect outcomes for people with meningioma, a common brain tumor. Researchers will enroll 3,000 adults who have been diagnosed with a meningioma. Participants will complete a survey and have their medical records…

This study aims to see if a special PET scan can detect a protein called PSMA in recurrent meningiomas, which are brain tumors that have come back after standard treatments. Researchers will scan 40 adult patients whose tumors have returned after surgery or radiation. If enough t…