MELANOMA STAGE IV
Clinical trials for MELANOMA STAGE IV explained in plain language.
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Bone drug boosts immunotherapy in advanced melanoma trial
Disease control CompletedThis study tested whether adding denosumab (a bone-strengthening drug) to standard immunotherapy (pembrolizumab or nivolumab) could help control advanced melanoma that has spread. Twenty-five adults with stage III or IV melanoma that had not been treated with immunotherapy before…
Matched conditions: MELANOMA STAGE IV
Phase: PHASE2 • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Disease control
Last updated May 17, 2026 01:00 UTC
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Experimental combo shows promise for Tough-to-Treat melanoma
Disease control CompletedThis study tested a new cancer vaccine (BNT111) combined with an immunotherapy drug (cemiplimab) in 184 people with advanced melanoma that had stopped responding to prior treatment. The goal was to see if the combination could shrink tumors better than either treatment alone. Par…
Matched conditions: MELANOMA STAGE IV
Phase: PHASE2 • Sponsor: BioNTech SE • Aim: Disease control
Last updated May 14, 2026 12:06 UTC