MELANOMA STAGE IV
Clinical trials for MELANOMA STAGE IV explained in plain language.
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New drug trial aims to unleash immune system against skin cancer
Disease control OngoingThis early-stage study is testing a new oral drug called SX-682 in people with advanced melanoma that has spread. The goal is to see if SX-682 can safely block certain cells that shield the tumor, allowing the patient's own immune system, boosted by an existing immunotherapy drug…
Matched conditions: MELANOMA STAGE IV
Phase: PHASE1 • Sponsor: Syntrix Biosystems, Inc. • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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New vaccine combo aims to boost Body's fight against advanced skin cancer
Disease control OngoingThis study is testing whether adding one of two experimental cancer vaccines (SCIB1 or iSCIB1+) to standard immunotherapy drugs can help people with advanced, inoperable melanoma. The goal is to see if the vaccines make the standard treatments work better and longer for patients.…
Matched conditions: MELANOMA STAGE IV
Phase: PHASE2 • Sponsor: Scancell Ltd • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Personalized vaccine trial aims to boost immune attack on advanced skin cancer
Disease control OngoingThis study is testing whether adding a personalized cancer vaccine called EVX-01 to a standard immunotherapy drug (pembrolizumab) can better control advanced melanoma that cannot be surgically removed. It involves about 17 adults with stage III or IV melanoma who have not yet rec…
Matched conditions: MELANOMA STAGE IV
Phase: PHASE2 • Sponsor: Evaxion Biotech A/S • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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New drug trial offers hope for patients with advanced cancers out of options
Disease control OngoingThis early-stage study is testing a new drug called ST101 in patients with advanced solid tumors that cannot be surgically removed and have spread. The trial aims to find a safe and effective dose for cancers including glioblastoma, melanoma, breast cancer, and prostate cancer in…
Matched conditions: MELANOMA STAGE IV
Phase: PHASE1, PHASE2 • Sponsor: Sapience Therapeutics • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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New hope for cancer patients suffering devastating drug side effect
Disease control OngoingThis study tests whether the drug infliximab works better than standard steroid treatment to control severe colon inflammation (colitis) caused by cancer immunotherapy drugs. The trial involves 42 adults with advanced skin cancer who developed this serious side effect while recei…
Matched conditions: MELANOMA STAGE IV
Phase: PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Doctors test direct brain injection to fight advanced cancer spread
Disease control OngoingThis early-stage study is testing whether injecting cancer-fighting drugs directly into the fluid around the brain and spine, along with standard IV treatment, can help control cancer that has spread to those areas. The trial involves 26 adults with advanced lung cancer or melano…
Matched conditions: MELANOMA STAGE IV
Phase: PHASE1 • Sponsor: University of Zurich • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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Double attack on melanoma: trial tests powerful drug combo before surgery
Disease control OngoingThis study compares two immunotherapy approaches given before surgery for advanced melanoma that can still be removed. Patients receive either one immunotherapy drug or a combination of two drugs for 6 weeks before their operation, followed by additional treatment afterward. The …
Matched conditions: MELANOMA STAGE IV
Phase: PHASE2 • Sponsor: Diwakar Davar • Aim: Disease control
Last updated Mar 18, 2026 18:25 UTC
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Tracking the hidden toll: study maps immunotherapy side effects in cancer survivors
Knowledge-focused OngoingThis study observes melanoma survivors who have completed surgery and are receiving immunotherapy drugs to prevent cancer return. Researchers follow 126 patients for two years to track side effects, symptoms like fatigue and depression, and quality of life. The goal is to underst…
Matched conditions: MELANOMA STAGE IV
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:01 UTC