MELANOMA STAGE IV
Clinical trials for MELANOMA STAGE IV explained in plain language.
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New vaccine combo shows promise for hard-to-treat melanoma
Disease control CompletedThis phase 2 trial tested a combination of an experimental cancer vaccine (BNT111) and an immunotherapy drug (cemiplimab) in 184 adults with advanced melanoma that no longer responded to standard immunotherapy. Participants were randomly assigned to receive the combination or eit…
Matched conditions: MELANOMA STAGE IV
Phase: PHASE2 • Sponsor: BioNTech SE • Aim: Disease control
Last updated Jun 16, 2026 12:54 UTC
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Bone drug may supercharge immunotherapy against tough melanoma
Disease control CompletedThis study tested whether adding denosumab (a bone-strengthening drug) to standard immunotherapy (pembrolizumab or nivolumab) could help control advanced melanoma that has spread. Researchers enrolled 25 adults with stage III or IV melanoma who had not received prior immunotherap…
Matched conditions: MELANOMA STAGE IV
Phase: PHASE2 • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 15, 2026 19:08 UTC