MDS
Clinical trials for MDS explained in plain language.
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New hope for rare blood cancers: fedratinib shows promise in early trial
Disease control CompletedThis study tested a drug called fedratinib in 25 adults with rare blood cancers (MDS/MPN and CNL). The goal was to see if the drug could shrink the spleen and improve blood counts. While not a cure, the treatment aims to control the disease and reduce symptoms.
Matched conditions: MDS
Phase: PHASE2 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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Pill may replace shots for blood cancer patients, study finds
Disease control CompletedThis study tested whether an oral medication (CC-486) could help elderly patients with a serious blood disorder called myelodysplastic syndrome (MDS) maintain their improvement after initial injectable treatment. Eleven patients who had responded to injectable azacitidine switche…
Matched conditions: MDS
Phase: PHASE2 • Sponsor: University of Florence • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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New hope for tough blood cancers? early trial tests LYT-200
Disease control CompletedThis early-stage study tested a new drug called LYT-200 in 101 adults whose acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS) had come back or stopped responding to treatment. The main goals were to check the drug's safety and find the right dose. While not…
Matched conditions: MDS
Phase: PHASE1 • Sponsor: PureTech • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Personalized mutation tracking could spot relapse sooner in bone marrow cancer patients
Knowledge-focused CompletedThis study looked at 308 people with myelodysplastic syndromes (MDS) who had a stem cell transplant. Researchers identified each patient's unique genetic mutations and then monitored those mutations in blood and bone marrow samples after transplant. The goal was to see if rising …
Matched conditions: MDS
Sponsor: Nordic MDS Group • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC