MANIA
Clinical trials for MANIA explained in plain language.
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New pill aims to tame bipolar mania without lifelong side effects?
Symptom relief Recruiting nowThis study tests an experimental drug, NBI-1117568, to see if it can reduce manic symptoms in adults with bipolar I disorder who are hospitalized for a manic episode. About 150 participants will receive either the drug or a placebo for 21 days. The main goal is to measure changes…
Matched conditions: MANIA
Phase: PHASE2 • Sponsor: Neurocrine Biosciences • Aim: Symptom relief
Last updated May 17, 2026 06:23 UTC
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New hope for bipolar mania: KarXT trial launches
Symptom relief Recruiting nowThis study tests whether adding the drug KarXT to standard mood stabilizers (lithium, valproate, or lamotrigine) can better control manic episodes in people with Bipolar I disorder. About 424 adults hospitalized for mania will receive either KarXT or a placebo for 5 weeks. The ma…
Matched conditions: MANIA
Phase: PHASE3 • Sponsor: Bristol-Myers Squibb • Aim: Symptom relief
Last updated May 13, 2026 16:03 UTC