MANIA
Clinical trials for MANIA explained in plain language.
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New hope for controlling bipolar manic episodes
Disease control Recruiting nowThis study is testing whether adding an investigational medication called KarXT to standard mood stabilizers helps reduce manic symptoms in people with Bipolar I disorder. Researchers will compare KarXT against a placebo in 424 hospitalized adults currently experiencing a manic e…
Matched conditions: MANIA
Phase: PHASE3 • Sponsor: Bristol-Myers Squibb • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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New hope for controlling severe bipolar mania
Disease control Recruiting nowThis study is testing whether a new investigational medicine called NBI-1117568 can help reduce severe manic symptoms in adults with bipolar I disorder who are currently hospitalized for a manic episode. The trial will compare the medicine to a placebo (an inactive substance) in …
Matched conditions: MANIA
Phase: PHASE2 • Sponsor: Neurocrine Biosciences • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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Scientists track mental health drugs from mom to baby
Knowledge-focused Recruiting nowThis study aims to understand how pregnancy and breastfeeding affect long-acting injectable antipsychotic medications used for conditions like schizophrenia. Researchers will measure drug levels in the blood of pregnant and breastfeeding women, and also check how much of the medi…
Matched conditions: MANIA
Sponsor: University of Liverpool • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:10 UTC