MANIA
Clinical trials for MANIA explained in plain language.
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New hope for bipolar mania: KarXT trial launches
Disease control Recruiting nowThis study tests whether adding KarXT to standard mood stabilizers (lithium, valproate, or lamotrigine) helps control manic episodes in people with bipolar I disorder. About 424 adults hospitalized for mania will receive either KarXT or a placebo for 5 weeks. The main goal is to …
Matched conditions: MANIA
Phase: PHASE3 • Sponsor: Bristol-Myers Squibb • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
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New pill aims to tame manic episodes in bipolar disorder
Symptom relief Recruiting nowThis study tests an experimental drug called NBI-1117568 for adults with bipolar I disorder who are hospitalized for a manic episode. Half of the 150 participants will get the drug, half a placebo, to see if it safely reduces manic symptoms over 21 days. The goal is to find a new…
Matched conditions: MANIA
Phase: PHASE2 • Sponsor: Neurocrine Biosciences • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC