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MANIA

Clinical trials for MANIA explained in plain language.

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Trials to join now! 2 Completed 2
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  • New hope for bipolar mania: KarXT trial launches

    Symptom relief Recruiting now

    This study tests whether adding the drug KarXT to standard mood stabilizers (lithium, valproate, or lamotrigine) can better control manic episodes in people with Bipolar I disorder. About 424 adults hospitalized for mania will receive either KarXT or a placebo for 5 weeks. The ma…

    Matched conditions: MANIA

    Phase: PHASE3 • Sponsor: Bristol-Myers Squibb • Aim: Symptom relief

    Last updated May 13, 2026 16:03 UTC

  • New pill aims to tame mania in bipolar patients

    Symptom relief Recruiting now

    This study tests an experimental drug, NBI-1117568, to see if it can reduce manic symptoms in adults with bipolar I disorder who are hospitalized for a manic episode. About 150 participants will receive either the drug or a placebo, and doctors will measure changes in mania score…

    Matched conditions: MANIA

    Phase: PHASE2 • Sponsor: Neurocrine Biosciences • Aim: Symptom relief

    Last updated Apr 29, 2026 15:02 UTC

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