MANIA
Clinical trials for MANIA explained in plain language.
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New hope for bipolar mania: KarXT trial launches
Symptom relief Recruiting nowThis study tests whether adding the drug KarXT to standard mood stabilizers (lithium, valproate, or lamotrigine) can better control manic episodes in people with Bipolar I disorder. About 424 adults hospitalized for mania will receive either KarXT or a placebo for 5 weeks. The ma…
Matched conditions: MANIA
Phase: PHASE3 • Sponsor: Bristol-Myers Squibb • Aim: Symptom relief
Last updated May 13, 2026 16:03 UTC
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New pill aims to tame mania in bipolar patients
Symptom relief Recruiting nowThis study tests an experimental drug, NBI-1117568, to see if it can reduce manic symptoms in adults with bipolar I disorder who are hospitalized for a manic episode. About 150 participants will receive either the drug or a placebo, and doctors will measure changes in mania score…
Matched conditions: MANIA
Phase: PHASE2 • Sponsor: Neurocrine Biosciences • Aim: Symptom relief
Last updated Apr 29, 2026 15:02 UTC